4-Chloro-3-iodo-1-(4-Methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine
- Product Name
- 4-Chloro-3-iodo-1-(4-Methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine
- CAS No.
- 1246349-97-2
- Chemical Name
- 4-Chloro-3-iodo-1-(4-Methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine
- Synonyms
- 4-Chloro-3-iodo-1-(4-methoxybenzyl);4-Chloro-3-iodo-1-(4-Methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine;1-(4-methoxybenzyl)-4-chloro-3-iodo-1H-pyrazolo[4,3-c]pyridine;4-Chloro-3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[4,3-c]pyridi...;4-chloro-3-iodo-1-[(4-methoxyphenyl)methyl]pyrazolo[4,3-c]pyridine;4-Chloro-3-iodo-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo[4,3-c]pyridine;1H-Pyrazolo[4,3-c]pyridine, 4-chloro-3-iodo-1-[(4-methoxyphenyl)methyl]-;4-Chloro-3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine - [C72336]
- CBNumber
- CB82563156
- Molecular Formula
- C14H11ClIN3O
- Formula Weight
- 399.61
- MOL File
- 1246349-97-2.mol
4-Chloro-3-iodo-1-(4-Methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine Property
- Boiling point:
- 526.5±50.0 °C(Predicted)
- Density
- 1.77
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 3.54±0.30(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C601760
- Product name
- 4-Chloro-3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- X9603
- Product name
- 4-Chloro-3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine
- Packaging
- 250mg
- Price
- $317
- Updated
- 2021/12/16
- Product number
- 075330
- Product name
- 4-Chloro-3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $416
- Updated
- 2021/12/16
- Product number
- HCH0366054
- Product name
- 4-CHLORO-3-IODO-1-(4-METHOXYBENZYL)-1H-PYRAZOLO[4,3-C]PYRIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.7
- Updated
- 2021/12/16
- Product number
- 075330
- Product name
- 4-Chloro-3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1197
- Updated
- 2021/12/16
4-Chloro-3-iodo-1-(4-Methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine Chemical Properties,Usage,Production
Synthesis
1186647-69-7
824-94-2
1246349-97-2
4-Chloro-3-iodo-1H-pyrazolo[4,3-c]pyridine (2.00 g, 7.17 mmol) and 1-(chloromethyl)-4-methoxybenzene (2.24 g, 14.3 mmol) were used as raw materials, and 4-chloro-3-iodo-1H-pyrazolo[4,3-c]pyridine was solubilized in dry DMF (30 mL), followed by the addition of KOH (0.800 g 14.3 mmol) and 1-(chloromethyl)-4-methoxybenzene. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the crude product obtained was purified by silica gel column chromatography with the eluent being petroleum ether/ethyl acetate (gradient from 10:1 to 8:1, v/v) to afford the target compound 4-chloro-3-iodo-1-(4-methoxyphenyl)-1H-pyrazolo[4,3-c]pyridine as a white solid (2.4 g, 82% yield).
References
[1] Patent: WO2013/139882, 2013, A1. Location in patent: Page/Page column 62
[2] Patent: US2014/288043, 2014, A1. Location in patent: Paragraph 0329
[3] Patent: WO2012/38743, 2012, A1. Location in patent: Page/Page column 82-83
[4] Patent: WO2017/215600, 2017, A1. Location in patent: Page/Page column 32-33
4-Chloro-3-iodo-1-(4-Methoxybenzyl)-1H-pyrazolo[4,3-c]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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