3-(PYRIMIDIN-2-YL)BENZOIC ACID

Product Name: 3-(PYRIMIDIN-2-YL)BENZOIC ACID
CAS No.: 579476-26-9
Chemical Name: 3-(PYRIMIDIN-2-YL)BENZOIC ACID
Synonyms: P-016;AKOS BAR-2338;3-(2-Pyrimidinyl)benzoic acid;2-(3-Carboxyphenyl)pyrimidine;3-(PYRIMIDIN-2-YL)BENZOIC ACID;3-Pyrimidin-2-yl-benzoicacid95%;Benzoic acid, 3-(2-pyrimidinyl)-;3-(PYRIMIDIN-2-YL)BENZOIC ACID ISO 9001：2015 REACH
CBNumber: CB8256632
Molecular Formula: C11H8N2O2
Formula Weight: 200.19
MOL File: 579476-26-9.mol

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
Hazard Note: Irritant
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 071830
Product name: 3-Pyrimidin-2-yl-benzoic acid
Purity: 95+%
Packaging: 1g
Price: $157
Updated: 2021/12/16

Apolloscientific

Product number: OR6233
Product name: 3-(Pyrimidin-2-yl)benzoicacid
Purity: 95%
Packaging: 1g
Price: $167
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H21-1-5X
Product name: 3-(Pyrimidin-2-yl)benzoic acid
Purity: 95%
Packaging: 1g
Price: $184
Updated: 2021/12/16

AK Scientific

Product number: W7123
Product name: 3-Pyrimidin-2-yl-benzoicacid
Packaging: 5g
Price: $308
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: COR0002526
Product name: 3-(PYRIMIDIN-2-YL)BENZOIC ACID
Purity: 95.00%
Packaging: 250MG
Price: $432.25
Updated: 2021/12/16

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3-(PYRIMIDIN-2-YL)BENZOIC ACID Chemical Properties,Usage,Production

Synthesis

1722-12-9

269409-73-6

579476-26-9

Pinacol ester of 3-carboxyphenylboronic acid (1 mmol), 2-chloropyrimidine (1.5 eq.) and Cs2CO3 (4.4 eq.) were added to a degassed DMF:H2O (10:1 ratio, 0.3 M) solution under nitrogen atmosphere. The mixture was degassed once and then Pd(PPh3)4 (5% molar ratio) was added. The reaction mixture was heated to 110°C. After completion of the reaction, the solvent was removed under vacuum to give a dark colloidal residue. The residue was dissolved in EtOAc and H2O and then acidified with 2 M HCl to pH 2. The organic layer was separated and the aqueous layer was further extracted with EtOAc (2 times). The organic layers were combined, dried with MgSO4 and concentrated in vacuum to obtain the residue. The residue was dried in vacuum and subsequently purified by fast chromatography using 10-30% EtOAc/petroleum ether and 1% acetic acid as eluent to give the target compound 3-pyrimidin-2-yl-benzaldehyde. The compound was prepared as a white solid (79% yield) by Suzuki coupling reaction.1H NMR (400 MHz, DMSO-d6) δ 8.99 (t, J = 1.5Hz, 1H), 8.95 (d, J = 4.9Hz, 2H), 8.61 (d, J = 7.9Hz, 1H), 8.09 (d, J = 7.7Hz, 1H), and 7.68 (d, J = 7.8 Hz, 1H), 7.50 (t, J = 4.9 Hz, 1H).LCMS retention time 2.96 min, m/z 201.1 [M + H].

References

[1] Patent: WO2016/198507, 2016, A1. Location in patent: Page/Page column 40; 51

3-(PYRIMIDIN-2-YL)BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(PYRIMIDIN-2-YL)BENZOIC ACID Suppliers

Belgium 1 China 32 Germany 3 India 1 United Kingdom 3 United States 9 Global 49

J & K SCIENTIFIC LTD.

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Shanghai yirong biology science and technology co., ltd

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Thermo Fisher Scientific

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NovoChemy Ltd.

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9ding chemical ( Shanghai) Limited

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SynAsst Chemical.

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Shanghai Raise Chemical Technology Co.,Ltd

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Chengdu Research Accelerators Technology Co., Ltd.

Tel: 028-64353063
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Amadis Chemical Company Limited

Tel: 571-89925085
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View Lastest Price from 3-(PYRIMIDIN-2-YL)BENZOIC ACID manufacturers

Dideu Industries Group Limited

Product: 3-(PYRIMIDIN-2-YL)BENZOIC ACID 579476-26-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-09

579476-26-9, 3-(PYRIMIDIN-2-YL)BENZOIC ACIDRelated Search:

4-(PYRIMIDIN-2-YL)BENZOIC ACID 4-PYRIMIDIN-5-YL-BENZOIC ACID,4-(2-(Methylthio)pyrimidin-5-yl)benzoic acid 4-(2-AMINOPYRIMIDIN-5-YL)BENZOIC ACID 3-(2-Aminopyrimidin-5-yl)benzoic acid (3-pyrimidin-2-ylphenyl)methanol 3-(PYRIMIDIN-2-YL)BENZOIC ACID 3-(PYRIMIDIN-2-YL)BENZALDEHYDE 3-(Pyrimidin-4-yl)benzoic acid 4-PYRIMIDIN-5-YL-BENZOIC ACID ETHYL ESTER 3-PYRIMIDIN-5-YL-BENZOIC ACID,3-(2-(Methylthio)pyrimidin-5-yl)benzoic acid,3-PYRIMIDIN-5-YL-BENZOIC ACID, 95+% 4-(2-Chloro-pyrimidin-4-yl)-benzoic acid 4-(Pyrimidin-4-yl)benzoic acid 2-(6-Chloro-pyrimidin-4-yl)-benzoic acid 4-(7-ETHYL-4-OXO-3,4,5,6,7,8-HEXAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-2-YL)BENZOIC ACID 4-(6-ACETYL-1,3,7-TRIMETHYL-2,4-DIOXO-1,2,3,4,5,8-HEXAHYDROPYRIDO[2,3-D]PYRIMIDIN-5-YL)BENZOIC ACID 2-(2-Chloro-pyrimidin-4-yl)-benzoic acid 4-(2-Chloro-pyrimidin-4-yl)-benzoic acid ethyl ester 4-(6-Chloro-pyrimidin-4-yl)-benzoic acid

AKOS BAR-2338

3-(PYRIMIDIN-2-YL)BENZOIC ACID

3-Pyrimidin-2-yl-benzoicacid95%

2-(3-Carboxyphenyl)pyrimidine

Benzoic acid, 3-(2-pyrimidinyl)-

3-(PYRIMIDIN-2-YL)BENZOIC ACID ISO 9001：2015 REACH

P-016

3-(2-Pyrimidinyl)benzoic acid

579476-26-9

Carboxylic Acids

Phenyls & Phenyl-Het

Carboxylic Acids

Phenyls & Phenyl-Het