2-chloroethanesulfonyl chloride
- Product Name
- 2-chloroethanesulfonyl chloride
- CAS No.
- 1622-32-8
- Chemical Name
- 2-chloroethanesulfonyl chloride
- Synonyms
- oroethanesuL;2-chloroethanesulfochloride;2-chloroethylsulfonylchloride;2-chloro-ethanesulfonylchlorid;2-CHLOROETHANESULFONYL CHLORIDE;2-chloroethanesulfochloride[qr];2-CHLOROETHANESULPHONYL CHLORIDE;(2-chloroethyl)sulphonyl chloride;beta-chloroethanesulfonylchloride;2-chloroethylsulfonylchloride[qr]
- CBNumber
- CB8257215
- Molecular Formula
- C2H4Cl2O2S
- Formula Weight
- 163.02
- MOL File
- 1622-32-8.mol
2-chloroethanesulfonyl chloride Property
- Melting point:
- 3 °C
- Boiling point:
- 84-86 °C15 mm Hg(lit.)
- Density
- 1.56 g/mL at 25 °C(lit.)
- vapor pressure
- 15 mm Hg ( 84 °C)
- refractive index
- n20/D 1.493(lit.)
- Flash point:
- >230 °F
- storage temp.
- Refrigerator
- form
- Liquid
- color
- Clear slightly yellow to brown
- Water Solubility
- Reacts with water.
- Sensitive
- Moisture Sensitive
- BRN
- 1751202
- InChI
- InChI=1S/C2H4Cl2O2S/c3-1-2-7(4,5)6/h1-2H2
- InChIKey
- VHCSBTPOPKFYIU-UHFFFAOYSA-N
- SMILES
- C(S(Cl)(=O)=O)CCl
- CAS DataBase Reference
- 1622-32-8(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Chloro-ethanesulfonyl chloride (1622-32-8)
Safety
- Hazard Codes
- T+
- Risk Statements
- 22-26-34-36
- Safety Statements
- 26-28-36/37/39-45-23
- RIDADR
- UN 3390 6.1/PG 1
- WGK Germany
- 3
- RTECS
- KI8060000
- F
- 10-19
- TSCA
- Y
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29049090
- Hazardous Substances Data
- 1622-32-8(Hazardous Substances Data)
- Toxicity
- mouse,LC50,inhalation,250mg/m3/4H (250mg/m3),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(6), Pg. 59, 1971.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H314Causes severe skin burns and eye damage
H330Fatal if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 302325
- Product name
- 2-Chloroethanesulfonyl chloride
- Purity
- 96%
- Packaging
- 5g
- Price
- $45.7
- Updated
- 2024/03/01
- Product number
- 302325
- Product name
- 2-Chloroethanesulfonyl chloride
- Purity
- 96%
- Packaging
- 25g
- Price
- $112
- Updated
- 2024/03/01
- Product number
- C1142
- Product name
- 2-Chloroethanesulfonyl Chloride
- Purity
- >95.0%(GC)(T)
- Packaging
- 25g
- Price
- $52
- Updated
- 2024/03/01
- Product number
- C1142
- Product name
- 2-Chloroethanesulfonyl Chloride
- Purity
- >95.0%(GC)(T)
- Packaging
- 100g
- Price
- $171
- Updated
- 2024/03/01
- Product number
- A15377
- Product name
- 2-Chloroethanesulfonyl chloride, 98%
- Packaging
- 10g
- Price
- $54.4
- Updated
- 2024/03/01
2-chloroethanesulfonyl chloride Chemical Properties,Usage,Production
Chemical Properties
CLEAR SLIGHTLY YELLOW TO BROWN LIQUID
Uses
2-Chloroethanesulfonyl chloride was used in one-pot sulfonylation/intramolecular thia-Michael protocol for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. It was also used in synthesis of vinyl sulfonamides with a furan, carbocyclic, semi cyclic or acyclic 1,3-diene moiety.
Application
As a precursor of the bis-electrophilic synthon vinylsulfonyl chloride, 2-chloroethanesulfonyl chloride can react with a wide range of bis-nucleophilic synthons, such as substituted 2-amino alcohols, to generate 7-membered sultams. This compound can be used in lieu of vinylsulfonyl chloride via a domino elimination– amidation reaction[1-2].
General Description
A liquid. Density 1.56 g / cm3. Flash point exceeds 230°F.
Air & Water Reactions
Reacts with water to produce corrosive and toxic gaseous hydrogen chloride.
Reactivity Profile
2-CHLOROETHANESULFONYL CHLORIDE is incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
References
[1] Qin Zang. “Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 1: A One-Pot Sulfonylation/Thia-Michael Protocol.” Heterocycles 86 2 (2012).
[2] Victor O Rogachev, Peter Metz. “Thermal and high pressure intramolecular Diels–Alder reaction of vinylsulfonamides.” Nature Protocols 1 6 (2007): 3076–3087.
2-chloroethanesulfonyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-chloroethanesulfonyl chloride manufacturers
- Product
- 2-CHLOROETHANESULFONYL CHLORIDE 1622-32-8
- Price
- US $0.00/kg
- Min. Order
- 10kg
- Purity
- 97%
- Supply Ability
- 20tons
- Release date
- 2024-09-23
- Product
- 2-CHLOROETHANESULFONYL CHLORIDE 1622-32-8
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08