3-BroMo-1-Methyl-pyrrolidine
Application- Product Name
- 3-BroMo-1-Methyl-pyrrolidine
- CAS No.
- 10603-45-9
- Chemical Name
- 3-BroMo-1-Methyl-pyrrolidine
- Synonyms
- 3-BroMo-1-Methyl-pyrrolidine;Pyrrolidine, 3-bromo-1-methyl-;3-Bromo-1-methylpyrrolidine,97%
- CBNumber
- CB82580454
- Molecular Formula
- C5H10BrN
- Formula Weight
- 164.04
- MOL File
- 10603-45-9.mol
3-BroMo-1-Methyl-pyrrolidine Property
- Boiling point:
- 153-159 °C
- Density
- 1.361 g/mL at 25 °C
- Flash point:
- 54 °C
- refractive index
- 1.4910
- storage temp.
- 2-8°C
- form
- Liquid
- pka
- 8.53±0.40(Predicted)
- color
- Yellow to brown
- Sensitive
- Moisture Sensitive
- InChI
- InChI=1S/C5H10BrN/c1-7-3-2-5(6)4-7/h5H,2-4H2,1H3
- InChIKey
- ZHUYTHOKJZSZQJ-UHFFFAOYSA-N
- SMILES
- N1(C)CCC(Br)C1
Safety
- Hazard Codes
- F,C
- Risk Statements
- 11-34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 2924 8(3) / PGIII
- WGK Germany
- WGK 3
- HazardClass
- 3
- PackingGroup
- Ⅲ
- Storage Class
- 3 - Flammable liquids
- Hazard Classifications
- Eye Irrit. 2
Flam. Liq. 3
Skin Corr. 1B
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 721867
- Product name
- 3-Bromo-1-methylpyrrolidine
- Purity
- 97%
- Packaging
- 500MG
- Price
- $89.5
- Updated
- 2023/06/20
- Product number
- B681050
- Product name
- 3-Bromo-1-methylpyrrolidine
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB159636
- Product name
- 3-Bromo-1-methylpyrrolidine
- Packaging
- 10mg
- Price
- $53
- Updated
- 2021/12/16
- Product number
- HCH0364390
- Product name
- 3-BROMO-1-METHYLPYRROLIDINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $152.25
- Updated
- 2021/12/16
- Product number
- FB159636
- Product name
- 3-Bromo-1-methylpyrrolidine
- Packaging
- 50mg
- Price
- $155
- Updated
- 2021/12/16
3-BroMo-1-Methyl-pyrrolidine Chemical Properties,Usage,Production
Application
3-Bromo-1-methylpyrrolidine is a colorless liquid and an important pharmaceutical intermediate. It can be used to prepare mGluR5 receptor allosteric modulators.
Synthesis
3-Hydroxy-1-methylpyrrolidine (5 g) was added in a 100 ml single-necked flask, n-hexane (50 ml) was cooled in an ice bath for 10 min, phosphorus tribromide (16.9 g) was added under cooling, and the temperature was raised to reflux for 2 h. Cooling was carried out. Neutralized to pH>8 by adding 25% KOH. extracted with ether. Combine the organic phases, add 1N hydrochloric acid 50ml, extract. Retain the aqueous phase, adjust pH>8, ether extract. Air dry. Obtained 3-bromo-1-methylpyrrolidine (1.1g).
3-BroMo-1-Methyl-pyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-BroMo-1-Methyl-pyrrolidine manufacturers
- Product
- 3-BroMo-1-Methyl-pyrrolidine 10603-45-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99.9%
- Supply Ability
- 200kg
- Release date
- 2020-01-10