5,6-DiHETE

Product Name: 5,6-DiHETE
CAS No.: 845673-97-4
Chemical Name: 5,6-DiHETE
Synonyms: 5,6-DiHETE;(±)5(6)-DiHETE;5,6-DiHETE Exclusive;VPXVODYVPILPRC-LTKCOYKYSA-N;5,6-dihydroxy-8(Z),11(Z),14(Z),17(Z)-ETA;5,6-dihydroxy-8(Z),11(Z),14(Z),17(Z)-eicosatetraenoic acid;8,11,14,17-Eicosatetraenoic acid, 5,6-dihydroxy-, (8Z,11Z,14Z,17Z)-
CBNumber: CB82590053
Molecular Formula: C20H32O4
Formula Weight: 336.47
MOL File: 845673-97-4.mol

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5,6-DiHETE Property

Boiling point:: 515.8±50.0 °C(Predicted)
Density: 1.040±0.06 g/cm3(Predicted)
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka: 4.68±0.10(Predicted)
form: Oil
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10467
Product name: (±)5(6)-DiHETE
Purity: ≥97%
Packaging: 25μg
Price: $105
Updated: 2024/03/01

Cayman Chemical

Product number: 10467
Product name: (±)5(6)-DiHETE
Purity: ≥97%
Packaging: 50μg
Price: $195
Updated: 2024/03/01

Cayman Chemical

Product number: 10467
Product name: (±)5(6)-DiHETE
Purity: ≥97%
Packaging: 100μg
Price: $369
Updated: 2024/03/01

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5,6-DiHETE Chemical Properties,Usage,Production

Description

Eicosapentaenoic acid (EPA; ) is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils. EPA is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases. (±)5(6)-DiHETE is a possible metabolite produced from EPA following epoxidation of the α-5 double bond. The biological activity of (±)5(6)-DiHETE has not been documented.

Uses

5,6-DiHETE is an anti-inflammatory lipid mediator derived from eicosapentaenoic acid (EPA). 5,6-DiHETE has the ability to suppress vascular hyperpermeability during inflammation and is used in the research of inflammatory diseases[1].

Definition

ChEBI: 5,6-DiHETE is a polyunsaturated fatty acid and a hydroxy fatty acid.

References

[1] Misato Kida, et al. A novel eicosapentaenoic acid-derived anti-inflammatory lipid mediator 5,6-DiHETE is abundant in blue back fish intestines. J Food Sci. 2020, 85, 7. DOI:10.1111/1750-3841.15179
[2] Kida M, et al. A novel eicosapentaenoic acid-derived anti-inflammatory lipid mediator 5,6-DiHETE is abundant in blue back fish intestines. J Food Sci. 2020 Jul;85(7):1983-1987. DOI:10.1111/1750-3841.15179

5,6-DiHETE Preparation Products And Raw materials

Raw materials

Preparation Products

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5,6-DiHETE Suppliers

China 24 United States 3 Global 27

Yichang Zhongyitai Trading Co., Ltd.

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845673-97-4, 5,6-DiHETERelated Search:

5,6-DiHETE

5,6-DiHETE Exclusive

VPXVODYVPILPRC-LTKCOYKYSA-N

5,6-dihydroxy-8(Z),11(Z),14(Z),17(Z)-eicosatetraenoic acid

8,11,14,17-Eicosatetraenoic acid, 5,6-dihydroxy-, (8Z,11Z,14Z,17Z)-

(±)5(6)-DiHETE

5,6-dihydroxy-8(Z),11(Z),14(Z),17(Z)-ETA

845673-97-4