5-BroMo-1H-pyrazole-3-carboxylic acid
- Product Name
- 5-BroMo-1H-pyrazole-3-carboxylic acid
- CAS No.
- 1328893-16-8
- Chemical Name
- 5-BroMo-1H-pyrazole-3-carboxylic acid
- Synonyms
- 5-Bromopyrazole-3-carboxylic Acid;5-BroMo-1H-pyrazole-3-carboxylic acid;1H-Pyrazole-3-carboxylic acid, 5-bromo-;5-BroMo-1H-pyrazole-3-carboxylic acid ISO 9001:2015 REACH
- CBNumber
- CB82594026
- Molecular Formula
- C4H3BrN2O2
- Formula Weight
- 190.98
- MOL File
- 1328893-16-8.mol
5-BroMo-1H-pyrazole-3-carboxylic acid Property
- Boiling point:
- 458.8±30.0 °C(Predicted)
- Density
- 2.129±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.59±0.10(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C4H3BrN2O2/c5-3-1-2(4(8)9)6-7-3/h1H,(H,6,7)(H,8,9)
- InChIKey
- OOKGNGYUNBYGEL-UHFFFAOYSA-N
- SMILES
- N1C(Br)=CC(C(O)=O)=N1
Safety
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- B568590
- Product name
- 5-Bromo-1H-pyrazole-3-carboxylicAcid
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR932764
- Product name
- 5-Bromo-1H-pyrazole-3-carboxylicacid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 119980
- Product name
- 5-Bromo-1H-pyrazole-3-carboxylic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $345
- Updated
- 2021/12/16
- Product number
- OR932764
- Product name
- 5-Bromo-1H-pyrazole-3-carboxylicacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $450
- Updated
- 2021/12/16
- Product number
- HCH0366732
- Product name
- 5-BROMO-1H-PYRAZOLE-3-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.05
- Updated
- 2021/12/16
5-BroMo-1H-pyrazole-3-carboxylic acid Chemical Properties,Usage,Production
Uses
5-Bromo-1H-pyrazole-3-carboxylic Acid is a useful reagent for the preparation of novel inhibitors of Rho/MRTF/SRF transcription as potential antifibrotics for scleroderma.
Synthesis
Dissolve 1.7g 3-methyl-5-bromopyrazole in 20ml 0.1M hydrochloric acid, put in 100mL three-necked flask, heated to 50; take about 1.5g potassium permanganate dissolved in 5mL water, use constant pressure funnel to add to the three-necked flask slowly; after the addition of material is completed, the reaction solution was stirred at 70 for 30min, and after that it was cooled down to room temperature, and pH of the solution was adjusted to acidic, 20mL EtOAc was added. EtOAc, extracted three times, the organic layer pH adjusted to alkaline, washed with water to obtain 5-bromo-1H-3-pyrazolecarboxylic acid, the yield was 85%.
5-BroMo-1H-pyrazole-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BroMo-1H-pyrazole-3-carboxylic acid manufacturers
- Product
- 5-Bromo-1H-pyrazole-3-carboxylic acid 1328893-16-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 10g
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2019-12-25
- Product
- 5-BroMo-1H-pyrazole-3-carboxylic acid 1328893-16-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-02