1-(2-BroMo-6-hydroxyphenyl)ethanone
- Product Name
- 1-(2-BroMo-6-hydroxyphenyl)ethanone
- CAS No.
- 55736-69-1
- Chemical Name
- 1-(2-BroMo-6-hydroxyphenyl)ethanone
- Synonyms
- 1-(2-Bromo-6-hydroxyphenyl);6’-Bromo-2’-hydroxyacetophenone;2'-bromo-6'-hydroxyacetophenone;6'-Bromo-2'-hydroxyacetophenone;1-(2-BroMo-6-hydroxyphenyl)ethanone;Ethanone, 1-(2-bromo-6-hydroxyphenyl)-;1-(2-bromo-6-hydroxyphenyl)ethan-1-one;1-(2-Bromo-6-hydroxyphenyl)ethan-1-one, 2-Acetyl-3-bromophenol
- CBNumber
- CB82595917
- Molecular Formula
- C8H7BrO2
- Formula Weight
- 215.04
- MOL File
- 55736-69-1.mol
1-(2-BroMo-6-hydroxyphenyl)ethanone Property
- Melting point:
- 106–108°C
- Boiling point:
- 276.8±25.0 °C(Predicted)
- Density
- 1.586±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- pka
- 9.20±0.10(Predicted)
- Appearance
- Off-white to light brown Solid
Safety
- HS Code
- 2914790090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B997250
- Product name
- 1-(2-Bromo-6-hydroxyphenyl)ethanone
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 119032
- Product name
- 1-(2-Bromo-6-hydroxyphenyl)ethanone
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- W6967
- Product name
- 1-(2-Bromo-6-hydroxyphenyl)ethanone
- Packaging
- 250mg
- Price
- $138
- Updated
- 2021/12/16
- Product number
- OR54370
- Product name
- 6'-Bromo-2'-hydroxyacetophenone
- Packaging
- 250mg
- Price
- $148
- Updated
- 2021/12/16
- Product number
- FB143617
- Product name
- 1-(2-Bromo-6-hydroxyphenyl)ethanone
- Packaging
- 250mg
- Price
- $200
- Updated
- 2021/12/16
1-(2-BroMo-6-hydroxyphenyl)ethanone Chemical Properties,Usage,Production
Preparation
Preparation by diazotization of 2-amino-6-bromoacetophenone, followed by hydrolysis of the obtained diazonium salt (50%).
Synthesis
35065-86-2
55736-69-1
General procedure for the synthesis of 1-(2-bromo-6-hydroxy-phenyl)-ethanone from phenyl 3-bromoacetate: Phenyl 3-bromoacetate (36.0 g, 167 mmol) was mixed with anhydrous AlCl3 (33.5 g, 251 mmol) and heated to 140-150 °C for 2 hours. After the reaction was completed, 100 mL of 5% HCl solution was added to the black solid and the mixture was heated on a boiling water bath until the solid was completely dissolved. After cooling to room temperature, the precipitated brown oil was extracted with CH2Cl2 (3 x 150 mL). The organic layer was separated by adding 300 mL of 5N NaOH solution to the combined organic layers and the precipitate formed dissolved in water. The aqueous phase was acidified with HCl to pH ~2 and extracted with EtOAc (5 x 150 mL). The organic extracts were combined and the solvents were evaporated after drying with Na2SO4 to give 1-(2-bromo-6-hydroxy-phenyl)-acetophenone as beige crystals (35.8 g, 99%).GC/MS data: m/z 214 (M+, calculated value C8H7BrO2 215.05), (calculated mass of a single substance as (M)* 213.96).1H NMR data ( DMSO-d6): δ 11.97 (s, 1H, OH), 7.78 (d, 1H, J = 8.3 Hz, Ar-H), 7.19 (d, 1H, J = 2.0 Hz, Ar-H), 7.13 (dd, 1H, J1 = 8.3 Hz, J2 = 2.0 Hz, Ar-H), 2.60 (s, 3H, CH3).
References
[1] Patent: WO2007/88450, 2007, A2. Location in patent: Page/Page column 21
1-(2-BroMo-6-hydroxyphenyl)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
1-(2-BroMo-6-hydroxyphenyl)ethanone Suppliers
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 5000
- Advantage
- 55
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 010-59484199 18611897322
- sales@eternalchem.com
- Country
- China
- ProdList
- 4383
- Advantage
- 60
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3764
- Advantage
- 58
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3731
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 15332490153
- Fax
- QQ 2725398181
- newprochem@126.com
- Country
- China
- ProdList
- 991
- Advantage
- 55
View Lastest Price from 1-(2-BroMo-6-hydroxyphenyl)ethanone manufacturers
- Product
- 1-(2-BroMo-6-hydroxyphenyl)ethanone 55736-69-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08