7-broMo-2-Methyl-1H-Indene
- Product Name
- 7-broMo-2-Methyl-1H-Indene
- CAS No.
- 880652-93-7
- Chemical Name
- 7-broMo-2-Methyl-1H-Indene
- Synonyms
- 7-bromo-2-methylindene;7-broMo-2-Methyl-1H-Indene;1H-Indene, 7-bromo-2-methyl-
- CBNumber
- CB82596237
- Molecular Formula
- C10H9Br
- Formula Weight
- 209.08
- MOL File
- 880652-93-7.mol
7-broMo-2-Methyl-1H-Indene Property
- Boiling point:
- 268℃
- Density
- 1.432
- Flash point:
- 118℃
- storage temp.
- 2-8°C
- InChI
- InChI=1S/C10H9Br/c1-7-5-8-3-2-4-10(11)9(8)6-7/h2-5H,6H2,1H3
- InChIKey
- OJSMHHJBFNVCAV-UHFFFAOYSA-N
- SMILES
- C1C2=C(C=CC=C2Br)C=C1C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B688955
- Product name
- 7-Bromo-2-methyl-1H-indene
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B688955
- Product name
- 7-Bromo-2-methyl-1H-indene
- Packaging
- 5g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 092392
- Product name
- 7-Bromo-2-methyl-1H-indene
- Purity
- 95+%
- Packaging
- 1g
- Price
- $279
- Updated
- 2021/12/16
- Product number
- 4035AC
- Product name
- 7-Bromo-2-methyl-1H-indene
- Packaging
- 5g
- Price
- $118
- Updated
- 2021/12/16
- Product number
- A331472
- Product name
- 7-Bromo-2-methyl-1H-indene
- Purity
- 97%
- Packaging
- 25g
- Price
- $153
- Updated
- 2021/12/16
7-broMo-2-Methyl-1H-Indene Chemical Properties,Usage,Production
Uses
7-Bromo-2-methyl-1H-indene is a reactant/reagent used in the synthesis of a broad range of ansa-zirconocenes containing bis(2-methyl-4-arylindenyl)dimethylsilane ligands via palladium-catalyzed reaction.
Synthesis
869063-68-3
880652-93-7
7-Bromo-2-methyl-1H-indene was synthesized as follows: to a solution of 116 g (0.52 mol) 4-bromo-6-chloro-2-methyl-2,3-dihydro-1H-inden-1-one in 950 mL THF-methanol (2:1, v/v) was added in batches of 38.3 g (1.02 mol) NaBH4 at -5 °C, and the addition process lasted for 2 h. (Note : the temperature must be kept below 0°C). After completion of the addition, the reaction mixture was stirred at room temperature overnight. Subsequently, the reaction mixture was poured into 1000 mL of ice water and acidified with 10% HCl to pH=4. The organic layer was separated and the aqueous layer was extracted with methyl tert-butyl ether (3 x 300 mL). The organic phases were combined, dried with K2CO3 and concentrated to dryness under reduced pressure. To the residue, 1500 mL of toluene was added and about 2 g of p-toluenesulfonic acid (p-TolSO3H) was added as a catalyst and the reaction was refluxed for 2 hours. After completion of the reaction, the mixture was cooled to room temperature, rapidly filtered through a short silica gel 60 column (40-63 μm, 60 mm diameter, 140 mm height) and the column was washed with 250 mL of toluene. The filtrate and washings were combined and concentrated to dryness under reduced pressure. Purification by fractional distillation afforded the target product 7-bromo-2-methyl-1H-indene, boiling point 104-108 °C/5 mmHg, yield 100 g (93%) as a colorless solid. Elemental analysis Calculated values (C10H9Br): C, 57.44; H, 4.34. Measured values: C, 57.59; H, 4.40. 1H NMR (CDCl3) δ: 7.23 (dd, J = 7.9 Hz, J = 1.0 Hz, 1H, 6-H), 7.18 (dd, J = 7.4 Hz, J = 1.0 Hz, 1H, 4-H), 7.10 (m, 1H, 4-H). 7.10 (m, 1H, 5-H), 6.51 (m, 1H, 3-H), 3.28 (m, 2H, 1,1'-H), 2.17 (s, 3H, 2-Me).13C NMR (CDCl3) δ: 147.3, 146.8, 143.3, 128.2, 127.1, 126.6, 118.7, 118.3. 44.2, 16.7.
References
[1] Patent: US2007/135595, 2007, A1
[2] Patent: US2007/135596, 2007, A1
7-broMo-2-Methyl-1H-Indene Preparation Products And Raw materials
Raw materials
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View Lastest Price from 7-broMo-2-Methyl-1H-Indene manufacturers
- Product
- 7-broMo-2-Methyl-1H-Indene 880652-93-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-15
- Product
- 7-broMo-2-Methyl-1H-Indene 880652-93-7
- Price
- US $10.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-28
- Product
- 7-broMo-2-Methyl-1H-Indene 880652-93-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%HPLC
- Supply Ability
- 10Tons
- Release date
- 2020-02-19