ChemicalBook > CAS DataBase List > (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid

(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid

Product Name
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid
CAS No.
220352-36-3
Chemical Name
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid
Synonyms
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid;Ticagrelor-22;Ticagerelor Impurity;Ticagrelor Related Compound 28;(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid;(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylicaci;Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, (1R,2R)-;(1R-2R)-2-(3,4-DIFLUOROPHENYL)CYCLOPROPANECARBOXYLIC ACID CAS 220352-36-3;Ticagrelor impurity 33/(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
CBNumber
CB82599546
Molecular Formula
C10H8F2O2
Formula Weight
198.17
MOL File
220352-36-3.mol
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(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid Property

Melting point:
78 - 81°C
Boiling point:
308.1±42.0 °C(Predicted)
Density 
1.435±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)
pka
4.53±0.10(Predicted)
form 
Solid
color 
Off-White
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Safety

HS Code 
2916200090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D447015
Product name
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylicAcid
Packaging
100mg
Price
$185
Updated
2021/12/16
TRC
Product number
D447015
Product name
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylicAcid
Packaging
500mg
Price
$460
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0032247
Product name
(1R,2R)-2-(3,4-DIFLUOROPHENYL)CYCLOPROPANECARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$502.22
Updated
2021/12/16
Apolloscientific
Product number
PC421187
Product name
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylicacid
Purity
97%
Packaging
100mg
Price
$699
Updated
2021/12/16
AK Scientific
Product number
2834AH
Product name
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylicacid
Packaging
2.5g
Price
$1109
Updated
2021/12/16
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(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid Chemical Properties,Usage,Production

Uses

(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylic Acid is an intermediate used to prepare AZD6140 as an orally active reversible P2Y12 receptor antagonist for prevention of thrombosis. It is also used to synthesize triazolopyrimidine derivatives as P2T receptor antagonists.

(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid Suppliers

China 98 India 3 United States 5 Global 106
Jiangsu Vcare PharmaTech Co., Ltd.
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View Lastest Price from (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid manufacturers

Career Henan Chemical Co
Product
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid 220352-36-3
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-03

220352-36-3, (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acidRelated Search:

Ticagrelor iMpurity (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol Ticagrelor Related Compound 44 4-Chloro-2-propylsulfanyl-pyrimidine 1,2-Cyclopentanediol, 3-[7-aMino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyriMidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)- TRANSAMINE Ticagrelor Related Compound 3 (3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2- 2-(((3aR,4S,6R,6aS)-6-(7-aMino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2-diMethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol Ticagrelor Sulfone (2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid (2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidine-2-carboxylic acid Cyclopropanamine,2-(3,4-difluorophenyl)-(1R,2S) -(2R,3R)-2,3-dihydroxybutanedioate (1:1) (1R,2R,3S,5R)-3-(7-((1S,2R)-2-(3,4-difluorophenyl)cyclopropylaMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (3aS,4R,6S,6aR)-6-AMinotetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-ol (1S,2S,3R,5S)-3-(7-hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol AR-C 124910XX 2-[[(3aR,4S,6R,6aS)-6-(7-azanyl-5-propylsulfanyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol

  • (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid
  • (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
  • Ticagrelor Related Compound 28
  • Ticagerelor Impurity
  • Ticagrelor-22
  • Ticagrelor impurity 33/(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
  • Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, (1R,2R)-
  • (1R-2R)-2-(3,4-DIFLUOROPHENYL)CYCLOPROPANECARBOXYLIC ACID CAS 220352-36-3
  • (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylicaci
  • 220352-36-3