AG-L-5968

Product Name: AG-L-5968
CAS No.: 793035-88-8
Chemical Name: AG-L-5968
Synonyms: CS-280;AG-L-5968;AG-L-59687;AG-L 59687;AG-L59687;α-D-Glucopyranoside, 8-[2-amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purin-9-yl]octyl;8-[2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purin-9-yl]octyl-alpha-D-glucopyranoside
CBNumber: CB82603692
Molecular Formula: C24H34BrN5O7S
Formula Weight: 616.53
MOL File: 793035-88-8.mol

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AG-L-5968 Property

Boiling point:: 847.4±75.0 °C(Predicted)
Density: 1.70
pka: 12.95±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd

Product number: orb146105
Product name: AG-L-59687
Purity: >98%
Packaging: 100mg
Price: $615.4
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb146105
Product name: AG-L-59687
Purity: >98%
Packaging: 250mg
Price: $1208.7
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb146105
Product name: AG-L-59687
Purity: >98%
Packaging: 1g
Price: $2395.3
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0001399
Product name: 2-(8-[2-AMINO-6-(4-BROMO-THIOPHEN-2-YLMETHOXY)-PURIN-9-YL]-OCTYLOXY)-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL
Purity: 95.00%
Packaging: 1KG
Price: $6745.2
Updated: 2021/12/16

DC Chemicals

Product number: DC2063
Product name: AG-L-59687
Purity: >98%
Packaging: 100mg
Price: $400
Updated: 2021/12/16

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AG-L-5968 Chemical Properties,Usage,Production

Uses

O6BTG-C8-αGlu is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor with an IC50 of 0.45 μM. At a concentration of 0.1 μM, O6BTG-C8-αGlu can completely inhibit MGMT in HeLaS3 cells. Even when applied chronically at high doses (up to 20 μM), it does not exhibit cytotoxicity. O6BTG-C8-αGlu is suitable for research on MGMT-related cancer diseases[1].

References

[1] Kaina B, et al. Inhibition of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors: comparison with nonconjugated inhibitors and effect on fotemustine and temozolomide-induced cell death. J Pharmacol Exp Ther. 2004 Nov;311(2):585-93. DOI:10.1124/jpet.104.071316

AG-L-5968 Preparation Products And Raw materials

Raw materials

Preparation Products

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AG-L-5968 Suppliers

China 25 United States 2 Global 27

AdooQ BioScience, LLC

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Shanghai HuanChuan Industry Co.,Ltd.

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AdooQ Bioscience CHINA

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SPIRO PHARMA

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Shanghai Biopharmaleader Co., Ltd.

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Changzhou Chenhong Biotechnology Co., Ltd.

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Cckinase, Inc.

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Absin Bioscience Inc.

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Adooq Bioscience LLC

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ShenZhen Trendseen Biological Technology Co.,Ltd.

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Email: trendseenbio@gmail.com
Country: China
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793035-88-8, AG-L-5968Related Search:

AG-L-5968

AG-L-59687

8-[2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purin-9-yl]octyl-alpha-D-glucopyranoside

AG-L 59687;AG-L59687

CS-280

α-D-Glucopyranoside, 8-[2-amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purin-9-yl]octyl

793035-88-8