4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene
- Product Name
- 4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene
- CAS No.
- 335013-18-8
- Chemical Name
- 4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene
- Synonyms
- 4-Bromo-2-(trifluoromethyl)benzyl bromide 95%;4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene;Benzene, 4-bromo-1-(bromomethyl)-2-(trifluoromethyl)-;4-bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene, 95%min
- CBNumber
- CB82609902
- Molecular Formula
- C8H5Br2F3
- Formula Weight
- 317.93
- MOL File
- 335013-18-8.mol
4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene Property
- Boiling point:
- 239.4±35.0 °C(Predicted)
- Density
- 1.885±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- liquid
- color
- Colorless
Safety
- HS Code
- 2902900000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B680928
- Product name
- 4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B680928
- Product name
- 4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- AK-94394
- Product name
- 4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene
- Purity
- 97+%
- Packaging
- 250mg
- Price
- $33
- Updated
- 2021/12/16
- Product number
- 232932
- Product name
- 4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene
- Purity
- 98%
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 1800-B-58
- Product name
- 4-Bromo-2-(trifluoromethyl)benzyl bromide
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene Chemical Properties,Usage,Production
Synthesis
86845-27-4
335013-18-8
General procedure for the synthesis of 4-bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene from 5-bromo-2-methyltrifluorotoluene: 5-bromo-2-methyltrifluorotoluene (25 g, 104.59 mmol), N-bromosuccinimide (18.62 g, 104.59 mmol) and benzoyl peroxide (1.27 g, 5.23 mmol) were reacted in a A mixture in carbon tetrachloride (35 mL) was heated and reacted at 90 °C for 4 hours. Upon completion of the reaction, the mixture was cooled to 0 °C and filtered through a glass sand core funnel and the solids were washed with dichloromethane. The filtrates were combined and concentrated and subsequently purified by fast column chromatography (eluent: hexane/ethyl acetate, 0% to 5% ethyl acetate gradient) to give a clear oily product, which was crystallized after standing (33.26 g, 100% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 4.57 (s, 2H), 7.46 (d, J = 8.3 Hz, 1H), 7.67 (d, J = 8.3 Hz, 1H), 7.78 (s, 1H).
References
[1] Patent: WO2006/18725, 2006, A1. Location in patent: Page/Page column 208
[2] Journal of Labelled Compounds and Radiopharmaceuticals, 2015, vol. 58, # 5, p. 188 - 195
[3] Patent: WO2008/148867, 2008, A2. Location in patent: Page/Page column 37
[4] Patent: WO2009/23964, 2009, A1. Location in patent: Page/Page column 24
[5] Patent: WO2006/46593, 2006, A1. Location in patent: Page/Page column 235
4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene Preparation Products And Raw materials
Raw materials
Preparation Products
4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene Suppliers
- Tel
- --
- Fax
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- sales@apolloscientific.co.uk
- Country
- United Kingdom
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View Lastest Price from 4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene manufacturers
- Product
- 4-broMo-1-(broMoMethyl)-2-(trifluoroMethyl)benzene 335013-18-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25