ChemicalBook > CAS DataBase List > 3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile

3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile

Product Name
3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile
CAS No.
1153949-38-2
Chemical Name
3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile
Synonyms
Ruxolitinib Impurity N5;-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile;β-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile;3-cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]propanenitrile;1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile;racemic 3-cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
CBNumber
CB82614379
Molecular Formula
C17H26BN3O2
Formula Weight
315.22
MOL File
1153949-38-2.mol
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3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile Property

Boiling point:
471.8±25.0 °C(Predicted)
Density 
1.13
storage temp. 
2-8°C
solubility 
DCM, Methanol
form 
Solid
pka
1.71±0.10(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C989815
Product name
β-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile
Packaging
25mg
Price
$385
Updated
2021/12/16
Crysdot
Product number
CD00012782
Product name
3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
Purity
97%
Packaging
1g
Price
$430
Updated
2021/12/16
Chemenu
Product number
CM137368
Product name
3-cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
Purity
95+%
Packaging
1g
Price
$800
Updated
2021/12/16
Abosyn
Product number
21-2828
Product name
3-cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
Purity
95%-98%
Packaging
1g
Price
$900
Updated
2021/12/16
Chemenu
Product number
CM137368
Product name
3-cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
Purity
95+%
Packaging
5g
Price
$1921
Updated
2021/12/16
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3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile Chemical Properties,Usage,Production

Uses

β-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile is an intermediate in the synthesis of Ruxolitinib (R701995), a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.

3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile Suppliers

Nanjing zehe Pharmaceutical Technology Co., Ltd
Tel
17768115366
Email
henry124604479@163.com
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China
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255
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Bayee Biotech (Anqing) Co., Ltd.
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0556-5032306 18917961636
Fax
+86-556-5032307
Email
wtx@bayeebio.com
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China
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Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
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China
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9458
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Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
Fax
+86 21 50676805
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China
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Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
0371-13526885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
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China
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3978
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Jinan elephant international trading co., LTD
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13006575422@163.com
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China
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6355
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Aikon International Limited
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025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
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China
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15494
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Jinan Yaoyan Pharmaceutical Co., Ltd.
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Fax
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Email
jnyaoyan@163.com
Country
China
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3069
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Taizhou Ruishinuo Pharmaceutical Technology Co., Ltd.
Tel
0523-86848872 19952992164
Fax
0523-86848872
Email
725236090@qq.com
Country
China
ProdList
97
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58
Abydos Scientific
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025-84767922 18936879710
Email
sales@abydoscientific.com
Country
China
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View Lastest Price from 3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile manufacturers

Henan Fengda Chemical Co., Ltd
Product
3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile 1153949-38-2
Price
US $10.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-28

1153949-38-2, 3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrileRelated Search:


  • 3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile
  • racemic 3-cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
  • 3-cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]propanenitrile
  • 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
  • β-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile
  • -Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile
  • Ruxolitinib Impurity N5
  • 1153949-38-2
  • C17H26BN3O2