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GLIOVIRIN

Product Name
GLIOVIRIN
CAS No.
83912-90-7
Chemical Name
GLIOVIRIN
Synonyms
GLIOVIRIN;(1aS,12aS)-4,4aβ,8,9-Tetrahydro-4β-hydroxy-9β-(2-hydroxy-3,4-dimethoxyphenyl)-12H-8α,11aα-(iminomethano)-1aαH,7H-[1,2,4]dithiazepino[4,3-b]oxireno[e][1,2]benzoxazine-7,13-dione;12H-8,11a-(Iminomethano)-1aH,7H-[1,2,4]dithiazepino[4,3-b]oxireno[e][1,2]benzoxazine-7,13-dione, 4,4a,8,9-tetrahydro-4-hydroxy-9-(2-hydroxy-3,4-dimethoxyphenyl)-, (1aS,4R,4aS,8S,9R,11aR,12aS)-;(1AS-(1AALPHA,4BETA,4ABETA,8ALPHA,9BETA,11AALPHA,12AR*))-4,4A,8,9-TETRAHYDRO-4-HYDROXY-9-(2-HYDROXY-3,4-DIMETHOXYPHENYL)-12H-8,11-(IMINOMETHANO)-1AH,7H-(1,2,4)DITHIAZEPINO(4,3-B)OXIRENO(E)(1,2)BENZOXAZINE-7,13-DIONE
CBNumber
CB8261524
Molecular Formula
C20H20N2O8S2
Formula Weight
480.51
MOL File
83912-90-7.mol
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GLIOVIRIN Property

storage temp. 
Store at -20°C
solubility 
DMSO: soluble,Ethanol: soluble,Methanol: soluble
form 
A solid
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Safety

HS Code 
2941900000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28583
Product name
Gliovirin
Packaging
1mg
Price
$499
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0019200
Product name
GLIOVIRIN
Purity
95.00%
Packaging
5MG
Price
$502.56
Updated
2021/12/16
Apolloscientific
Product number
BIBR1047
Product name
Gliovirin
Packaging
1mg
Price
$522
Updated
2021/12/16
AK Scientific
Product number
4611ED
Product name
Gliovirin
Packaging
1mg
Price
$700
Updated
2021/12/16
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GLIOVIRIN Chemical Properties,Usage,Production

Description

Gliovirin is a fungal metabolite that has been found in T. harzianum and has fungicidal, antimicrobial and anti-inflammatory activities. It is active against the plant pathogenic fungus P. ultimum (MIC = 60 ng/ml) and the parasite T. brucei brucei (IC50 = 90 ng/ml), but has no effect on the plant pathogenic fungi R. solani, P. omnivorum, T. basicola, R. arrhizus, and V. dahliae or the bacteria B. thuringiensis, P. fluorescens, and X. malvacearum when used at concentrations up to 1,000 ng/ml. Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 (IC50 = 1 μM) and protein levels of IL-2 in Jurkat cells (IC50 = 5.2 μM).

References

[1] JAN RETHER. Inhibition of inducible tumor necrosis factor-alpha expression by the fungal epipolythiodiketopiperazine gliovirin.[J]. Biological Chemistry, 2007, 388 6: 627-637. DOI: 10.1515/bc.2007.066
[2] HOWELL C R, STIPANOVIC R. Gliovirin, a new antibiotic from Gliocladium virens, and its role in the biological control of Pythium ultimum[C]//57 1. 1983: 0. DOI: 10.1139/m83-053
[3] MASATO IWATSUKI. In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships[J]. Journal of Antibiotics, 2010, 63 10: 619-622. DOI: 10.1038/ja.2010.99

GLIOVIRIN Preparation Products And Raw materials

Raw materials

Preparation Products

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GLIOVIRIN Suppliers

China 10 Germany 2 United Kingdom 1 United States 2 Global 15
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Zhejiang Huida Biotech Co., LTD
Tel
0571-89903882 18679456698
Email
mingxinzhu@huidabiotech.com
Country
China
ProdList
2975
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
29668
Advantage
58
Zhejiang Huida Biotech Co., LTD
Tel
0571-0571-89903882 15990081639
Email
sunshixuan@huidabiotech.com
Country
China
ProdList
3705
Advantage
58
Guangzhou Yaoguang Technology Co., Ltd.
Tel
13020159086
Email
yangjue@ygfuture.com
Country
China
ProdList
424
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Shenzhen Campbell Biotechnology Co., Ltd.
Tel
18028747627
Country
CHINA
ProdList
191
Advantage
58

83912-90-7, GLIOVIRINRelated Search:

sec-Butyl disulfide CYCLO(-LEU-GLY) 2-(d-alpha-Methylphenethylamino)ethanethiol (S)-3-(2-HYDROXYETHYL)-2,5-DIKETOPIPERAZINE N-METHOXY-N-METHYL-3-PHENYL-PROPIONAMIDE GLIOVIRIN

  • GLIOVIRIN
  • (1aS,12aS)-4,4aβ,8,9-Tetrahydro-4β-hydroxy-9β-(2-hydroxy-3,4-dimethoxyphenyl)-12H-8α,11aα-(iminomethano)-1aαH,7H-[1,2,4]dithiazepino[4,3-b]oxireno[e][1,2]benzoxazine-7,13-dione
  • (1AS-(1AALPHA,4BETA,4ABETA,8ALPHA,9BETA,11AALPHA,12AR*))-4,4A,8,9-TETRAHYDRO-4-HYDROXY-9-(2-HYDROXY-3,4-DIMETHOXYPHENYL)-12H-8,11-(IMINOMETHANO)-1AH,7H-(1,2,4)DITHIAZEPINO(4,3-B)OXIRENO(E)(1,2)BENZOXAZINE-7,13-DIONE
  • 12H-8,11a-(Iminomethano)-1aH,7H-[1,2,4]dithiazepino[4,3-b]oxireno[e][1,2]benzoxazine-7,13-dione, 4,4a,8,9-tetrahydro-4-hydroxy-9-(2-hydroxy-3,4-dimethoxyphenyl)-, (1aS,4R,4aS,8S,9R,11aR,12aS)-
  • 83912-90-7
  • C20H20N2O8S2
  • Antibiotic