H-Aib-OBzl
- Product Name
- H-Aib-OBzl
- CAS No.
- 60421-20-7
- Chemical Name
- H-Aib-OBzl
- Synonyms
- aib-obzl.hcl;Benzyl αH-Aib-Obn.HCl;H-Aib-OBzl USP/EP/BP;Benzyl 2-amino-2-methylpropanoate HCl;Benzyl α-aminoisobutyrate hydrochloride;2-Methylalanine benzyl ester hydrochloride;Benzyl alpha-aMinoisobutyrate hydrochloride;Benzyl 2-amino-2-methylpropionate hydrochloride;2-Aminoisobutyric acid benzyl ester hydrochloride
- CBNumber
- CB82620071
- Molecular Formula
- C11H16ClNO2
- Formula Weight
- 229.70324
- MOL File
- 60421-20-7.mol
H-Aib-OBzl Property
- Melting point:
- 170-171℃
- storage temp.
- 2-8°C
- solubility
- H2O: soluble50mg/mL, clear, colorless
- form
- powder
- Appearance
- White to off-white Solid
- Water Solubility
- H2O: 50mg/mL, clear, colorless
- BRN
- 5149947
- InChI
- InChI=1S/C11H15NO2.ClH/c1-11(2,12)10(13)14-8-9-6-4-3-5-7-9;/h3-7H,8,12H2,1-2H3;1H
- InChIKey
- OXUUEIDXKLFLER-UHFFFAOYSA-N
- SMILES
- C(OCC1=CC=CC=C1)(=O)C(N)(C)C.[H]Cl
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 726354
- Product name
- Benzyl α-aminoisobutyrate hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 1g
- Price
- $504
- Updated
- 2023/06/20
- Product number
- AS88253
- Product name
- Benzyl 2-amino-2-methylpropanoate HCl
- Purity
- 95%
- Packaging
- 1g
- Price
- $79
- Updated
- 2021/12/16
- Product number
- CS-0096008
- Product name
- Benzyl2-amino-2-methylpropanoatehydrochloride
- Purity
- ≥97.0%
- Packaging
- 5g
- Price
- $134
- Updated
- 2021/12/16
- Product number
- AS88253
- Product name
- Benzyl 2-amino-2-methylpropanoate HCl
- Purity
- 95%
- Packaging
- 5G
- Price
- $217
- Updated
- 2021/12/16
- Product number
- CS-0096008
- Product name
- Benzyl2-amino-2-methylpropanoatehydrochloride
- Purity
- ≥97.0%
- Packaging
- 10g
- Price
- $218
- Updated
- 2021/12/16
H-Aib-OBzl Chemical Properties,Usage,Production
Chemical Properties
Benzyl 2-amino-2-methylpropanoate hydrochloride, also known as H-Aib-OBzl, is a white solid.
Uses
peptide synthesis
Preparation
A mixture of 2-amino-2- methylpropanoic acid (3 g, 29.1 mmol), benzyl alcohol (12 mL, 115 mmol), and p- toluenesulfonic acid monohydrate (5.53 g, 29.1 mmol) in toluene (40 mL) was heated under reflux overnight. Additional benzyl alcohol (12 mL, 115 mmol) was added and the reaction mixture was heated with a Dean Starck overnight. The reaction mixture was concentrated under reduced pressure and washed with diethyl ether. Diethyl ether was removed, and then the residue was dissolved in ethyl acetate and washed with a saturated aqueous NaHC03 solution. The organic layer was dried over Na2S04 and concentrated under reduced pressure. The resulting product was triturated with diethyl ether and HCI in dioxane. The solid was filtered, washed with diethyl ether and dried under reduced pressure to afford benzyl 2-amino-2-methylpropanoate hydrochloride (H-Aib-OBzl).
reaction suitability
reaction type: solution phase peptide synthesis
Waste Disposal
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
H-Aib-OBzl Preparation Products And Raw materials
Raw materials
Preparation Products
H-Aib-OBzl Suppliers
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View Lastest Price from H-Aib-OBzl manufacturers
- Product
- H-Aib-OBzl 60421-20-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-04-22
- Product
- Aib-obzl.HCL 60421-20-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%;99%
- Supply Ability
- 1T+
- Release date
- 2023-09-08