Faldaprevir

Product Name: Faldaprevir
CAS No.: 801283-95-4
Chemical Name: Faldaprevir
Synonyms: BI 201335;Faldaprevir;Faldaprevir-d7;Faldaprevir(BI 201335);BI201335; BI 201335; BI-201335;(1R,2S)-N-[(Cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-bromo-7-methoxy-2-[2-[(2-methyl-1-oxopropyl)amino]-4-thiazolyl]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethenyl-cyclopropanecarboxylic acid;Cyclopropanecarboxylic acid, N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-bromo-7-methoxy-2-[2-[(2-methyl-1-oxopropyl)amino]-4-thiazolyl]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethenyl-, (1R,2S)-;(1R,2S)-1-((2S,4R)-4-((8-Bromo-2-(2-isobutyramidothiazol-4-yl)-7-methoxyquinolin-4-yl)oxy)-1-((S)-2-(((cyclopentyloxy)carbonyl)amino)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-2-vinylcyclopropane-1-carboxylic acid
CBNumber: CB82627595
Molecular Formula: C40H49BrN6O9S
Formula Weight: 869.82
MOL File: 801283-95-4.mol

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Faldaprevir Property

solubility: DMSO:0.0(Max Conc. mg/mL);0.0(Max Conc. mM)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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Faldaprevir Chemical Properties,Usage,Production

Uses

Faldaprevir (BI 201335) is a potent, orally active and selective noncovalent inhibitor of NS3/4A protease of HCV (hepatitis C virus) genotypes 1a and 1b, with Ki values of 2.6 and 2.0 nM, respectively. Faldaprevir inhibits HCV RNA replication, with EC50 values of 6.5 and 3.1 nM, respectively. Faldaprevir has potent antiviral activity against chronic HCV infection[1][2].

References

[1] Llinàs-Brunet M, et al. Discovery of a potent and selective noncovalent linear inhibitor of the hepatitis C virus NS3 protease (BI 201335). J Med Chem. 2010 Sep 9;53(17):6466-76. DOI:10.1021/jm100690x
[2] Zeuzem S, et al. Faldaprevir (BI 201335), deleobuvir (BI 207127) and ribavirin oral therapy for treatment-naive HCV genotype 1: SOUND-C1 final results. Antivir Ther. 2013;18(8):1015-9. DOI:10.3851/IMP2567

Faldaprevir Preparation Products And Raw materials

Raw materials

Preparation Products

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Faldaprevir Suppliers

China 25 France 1 India 1 United States 2 Global 29

Shanghai Witofly Chemical Co.,Ltd

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Email: sales@witofly.com
Country: China
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AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
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Jinan Mingya Medical Technology Co., Ltd.

Tel: 0531-85828981
Fax: +86-531-85806006
Email: 864598798@qq.com
Country: China
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Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
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Raw material medicin reagent co.,Ltd

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Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
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Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
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Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.

Tel: 029-88380327 17691182729
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Email: 1018@dideu.com
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ProdList: 2011
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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Xi'an MC Biotech, Co., Ltd.

Tel: 029-89275612 +8618991951683
Fax: 8618991951683
Email: mcbio_sales@163.com
Country: China
ProdList: 2251
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View Lastest Price from Faldaprevir manufacturers

Career Henan Chemical Co

Product: Faldaprevir 801283-95-4
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2019-12-25

801283-95-4, FaldaprevirRelated Search:

Trastuzumab

BI 201335

Faldaprevir

Faldaprevir(BI 201335)

(1R,2S)-N-[(Cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-bromo-7-methoxy-2-[2-[(2-methyl-1-oxopropyl)amino]-4-thiazolyl]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethenyl-cyclopropanecarboxylic acid

BI201335; BI 201335; BI-201335

Faldaprevir-d7

Cyclopropanecarboxylic acid, N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-bromo-7-methoxy-2-[2-[(2-methyl-1-oxopropyl)amino]-4-thiazolyl]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethenyl-, (1R,2S)-

(1R,2S)-1-((2S,4R)-4-((8-Bromo-2-(2-isobutyramidothiazol-4-yl)-7-methoxyquinolin-4-yl)oxy)-1-((S)-2-(((cyclopentyloxy)carbonyl)amino)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-2-vinylcyclopropane-1-carboxylic acid

801283-95-4

C40H49BrN6O9S