ChemicalBook > CAS DataBase List > FGH-10019

FGH-10019

Product Name: FGH-10019
CAS No.: 1046045-61-7
Chemical Name: FGH-10019
Synonyms: FGH-10019;FGH10019, 10 mM in DMSO;FGH10019;FGH-10019;FGH 10019;FGH10019,FGH 10019,inhibit,Inhibitor,Fatty Acid Synthase (FASN);N-(4-(2-(2-propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide;Methanesulfonamide, N-[4-[2-(2-propyl-4-pyridinyl)-4-thiazolyl]phenyl]-
CBNumber: CB82627883
Molecular Formula: C18H19N3O2S2
Formula Weight: 373.49
MOL File: 1046045-61-7.mol

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FGH-10019 Property

Boiling point:: 578.4±60.0 °C(Predicted)
Density: 1.307±0.06 g/cm3(Predicted)
pka: 7.16±0.10(Predicted)
form: Solid
color: Light yellow to khaki

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-3637
Product name: FGH10019
Purity: 99.43%
Packaging: 5mg
Price: $330
Updated: 2021/12/16

ChemScene

Product number: CS-3637
Product name: FGH10019
Purity: 99.43%
Packaging: 10mg
Price: $480
Updated: 2021/12/16

ChemScene

Product number: CS-3637
Product name: FGH10019
Purity: 99.43%
Packaging: 50mg
Price: $1440
Updated: 2021/12/16

Crysdot

Product number: CD31004727
Product name: FGH10019
Purity: 98+%
Packaging: 5mg
Price: $243
Updated: 2021/12/16

Crysdot

Product number: CD31004727
Product name: FGH10019
Purity: 98+%
Packaging: 10mg
Price: $347
Updated: 2021/12/16

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FGH-10019 Chemical Properties,Usage,Production

Uses

FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM.

in vivo

FGH10019-treated chow is fed at a dose rate calculated to provide about 0.7 mg analog FGH10019 per day, at about 23 mg/kg body weight, to 5-wk-old male ob/ob mice weighing an average of appr 30 g. After 8 wk on the analog 24-treated chow, the mice gain 8-9 % less weight than control mice^[1].

References

[1] Kamisuki S, et al. Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. J Med Chem. 2011 Jul 14;54(13):4923-7. DOI:10.1021/jm200304y

FGH-10019 Preparation Products And Raw materials

Raw materials

Preparation Products

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1046045-61-7, FGH-10019Related Search:

FGH-10019

N-(4-(2-(2-propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide

FGH10019;FGH-10019;FGH 10019

Methanesulfonamide, N-[4-[2-(2-propyl-4-pyridinyl)-4-thiazolyl]phenyl]-

FGH10019,FGH 10019,inhibit,Inhibitor,Fatty Acid Synthase (FASN)

FGH10019, 10 mM in DMSO

1046045-61-7