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2'-O-t-ButyldiMethylsilyl adenosine

Product Name
2'-O-t-ButyldiMethylsilyl adenosine
CAS No.
69504-13-8
Chemical Name
2'-O-t-ButyldiMethylsilyl adenosine
Synonyms
2'-O-TBDMS-adenosine;2'-O-TBDMS adenosine;2'-O-t-ButyldiMethylsilyl adenosine;Adenosine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI)
CBNumber
CB82630812
Molecular Formula
C16H27N5O4Si
Formula Weight
381.5
MOL File
69504-13-8.mol
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2'-O-t-ButyldiMethylsilyl adenosine Property

Boiling point:
572.2±60.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
pka
13.13±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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2'-O-t-ButyldiMethylsilyl adenosine Chemical Properties,Usage,Production

Uses

2’-O-t-Butyldimethylsilyladenosine is a adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

2'-O-t-ButyldiMethylsilyl adenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-O-t-ButyldiMethylsilyl adenosine Suppliers

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69504-13-8, 2'-O-t-ButyldiMethylsilyl adenosineRelated Search:

Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]- 2'-O-(tert-butyldimethylsilyl)cytidine 3'-O-tert-Butyldimethylsilyladenosine 2'-O-(tert-butyldiMethylsilyl)uridine 2'-TBDMS-5-Me-rU 2'-O-(tert-butyl-dimethyl-silanyl)-guanosine Guanosine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI) INDEX NAME NOT YET ASSIGNED

  • 2'-O-TBDMS adenosine
  • 2'-O-t-ButyldiMethylsilyl adenosine
  • Adenosine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI)
  • 2'-O-TBDMS-adenosine
  • 69504-13-8
  • Nucleosides-2'-O-TBDMS Nucleosides