ChemicalBook > CAS DataBase List > 5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester

5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester

Product Name
5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester
CAS No.
330785-83-6
Chemical Name
5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester
Synonyms
RSYY（Lifitegrast)-4;Avanafil Impurity 64;5-Pyrimidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)m...;(S)-Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5;(S)-4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-(2-hydroxyMethyl-1-pyrrolidinyl)pyriMidine;ethyl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate;(S)-ethyl 4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)pyriMidine-5-carboxylate;ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylate;Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethy l)-1-pyrrolidinyl]-5-pyrimidinecarboxylate;5-Pyrimidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl
CBNumber
CB82638449
Molecular Formula
C20H25ClN4O4
Formula Weight
420.89
MOL File
330785-83-6.mol
More
Less

5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester Property

Boiling point:
607.5±65.0 °C(Predicted)
Density 
1.317±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C(protect from light)
pka
14.77±0.10(Predicted)
Appearance
White to off-white Solid
InChIKey
NUTJUOHYJBWTSH-AWEZNQCLSA-N
SMILES
C1(N2CCC[C@H]2CO)=NC=C(C(OCC)=O)C(NCC2=CC=C(OC)C(Cl)=C2)=N1
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

AK Scientific
Product number
0769DJ
Product name
Ethyl4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylate
Packaging
100mg
Price
$89
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0107443
Product name
ETHYL-4-(((3-CHLORO-4-METHOXYPHENYL)METHYL)AMINO)-2-((2S)-2-(HYDROXYMETHYL) PYRROLIDIN-1-YL)PYRIMIDINE-5-CARBOXYLATE
Purity
95.00%
Packaging
1MG
Price
$647.61
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0107443
Product name
ETHYL-4-(((3-CHLORO-4-METHOXYPHENYL)METHYL)AMINO)-2-((2S)-2-(HYDROXYMETHYL) PYRROLIDIN-1-YL)PYRIMIDINE-5-CARBOXYLATE
Purity
95.00%
Packaging
10MG
Price
$679.14
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0107443
Product name
ETHYL-4-(((3-CHLORO-4-METHOXYPHENYL)METHYL)AMINO)-2-((2S)-2-(HYDROXYMETHYL) PYRROLIDIN-1-YL)PYRIMIDINE-5-CARBOXYLATE
Purity
95.00%
Packaging
5MG
Price
$687.35
Updated
2021/12/16
Chemenu
Product number
CM132917
Product name
ethyl(S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Purity
95%
Packaging
5g
Price
$842
Updated
2021/12/16
More
Less

5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester Chemical Properties,Usage,Production

Uses

(S)-Ethyl 4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate is an avanafil related compound. Avanafil (A794670 ) is a potent and highly selective phosphodiesterase 5 inhibitor use in the treatment of erectile dysfunction.

5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester Suppliers

China 106 India 3 United States 3 Global 112
ChemFuture PharmaTech (Jiangsu) Ltd
Tel
5108538618
Fax
86 510 85386988-8017
Email
suger.wang@chemfuture.com
Country
China
ProdList
832
Advantage
65
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2827
Advantage
65
Beijing Ouhe Technology Co., Ltd
Tel
13552068683 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
11778
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Suzhou Zehou Biotechnology Co. , Ltd.
Tel
0512-68716880 19984816880
Fax
18075373931
Email
sales@growingchem.com
Country
China
ProdList
216
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5157
Advantage
50
China Nobel Chem Co., Limited
Tel
+86(0)21 60484900
Fax
+86(0)21 60484900
Country
China
ProdList
764
Advantage
50
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
1490
Advantage
62
More
Less

View Lastest Price from 5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester manufacturers

Career Henan Chemical Co
Product
5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester 330785-83-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98-100%
Supply Ability
100KG
Release date
2018-08-20
Shanghai Yingrui Biopharma Co., Ltd.
Product
(S)-4-(3-chloro-4- MethoxybenzylaMino)-5- ethoxycarbonyl-2-(2-hydroxyMethyl -1-pyrrolidinyl)pyriMidine 330785-83-6
Price
US $0.00/KG
Min. Order
0KG
Purity
99%
Supply Ability
100t
Release date
2018-03-06

330785-83-6, 5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl esterRelated Search:


  • 5-PyriMidinecarboxylic acid,4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-, ethyl ester
  • (S)-4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-(2-hydroxyMethyl-1-pyrrolidinyl)pyriMidine
  • 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-5-pyrimidinecarboxylic acid ethyl ester
  • (S)-ethyl 4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)pyriMidine-5-carboxylate
  • ethyl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
  • 5-Pyrimidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl
  • (S)-Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5
  • Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethy l)-1-pyrrolidinyl]-5-pyrimidinecarboxylate
  • 5-Pyrimidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)m...
  • Avanafil Impurity 64
  • RSYY（Lifitegrast)-4
  • ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylate
  • 330785-83-6
  • C20H25ClN4O4