1H-Indole, 6-broMo-2-Methyl-
- Product Name
- 1H-Indole, 6-broMo-2-Methyl-
- CAS No.
- 6127-19-1
- Chemical Name
- 1H-Indole, 6-broMo-2-Methyl-
- Synonyms
- NSC 115145;6-BroMo-2-Methylindole;1H-Indole, 6-broMo-2-Methyl-
- CBNumber
- CB82638883
- Molecular Formula
- C9H8BrN
- Formula Weight
- 210.07
- MOL File
- 6127-19-1.mol
1H-Indole, 6-broMo-2-Methyl- Property
- Melting point:
- 134.5-135.5℃
- Boiling point:
- 325.1±22.0 °C(Predicted)
- Density
- 1.563±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 16?+-.0.30(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B405243
- Product name
- 6-Bromo-2-methyl-1H-indole
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 119526
- Product name
- 6-Bromo-2-methyl-1H-indole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $335
- Updated
- 2021/12/16
- Product number
- HCH0352522
- Product name
- 6-BROMO-2-METHYL-1H-INDOLE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.94
- Updated
- 2021/12/16
- Product number
- 35259
- Product name
- 6-Bromo-2-methyl-1H-indole
- Purity
- 95+%
- Packaging
- 1000mg
- Price
- $620
- Updated
- 2021/12/16
- Product number
- Z4943
- Product name
- 6-Bromo-2-methylindole
- Packaging
- 10g
- Price
- $942
- Updated
- 2021/12/16
1H-Indole, 6-broMo-2-Methyl- Chemical Properties,Usage,Production
Synthesis
67-64-1
591-19-5
6127-19-1
General procedure for the synthesis of 6-bromo-2-methyl-1H-indole (CXXXIII): 3-bromoaniline (4 g, 0.041 mmol), copper(II) acetate monohydrate (14.0 g, 0.129 mmol), palladium(II) acetate (0.1 g, 0.000801 mmol), and acetone (100 mL) were combined in a dimethyl sulfoxide (50 mL) The solution was heated at 90 °C for 24 hours. After completion of the reaction, the reaction mixture was poured into cold water and extracted with ethyl acetate (2 x 250 mL). The organic layers were combined, washed sequentially with water and brine, and then dried over anhydrous sodium sulfate. The organic layer was concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography (100-200 mesh) to afford the target compound CXXXIII (1.3 mg, 27% yield) using hexane solution of 5% ethyl acetate as eluent. The product characterization data were as follows: 1H NMR (400 MHz, CDCl3): δ 7.83 (brs, 1H), 7.40 (s, 1H), 7.34 (d, J=8.3 Hz, 1H), 7.14 (dd, J=8.5,1.7 Hz, 1H), 6.17 (s, 1H), 2.41 (s, 3H); MS (ESI, positive mode) m/z 208/210 (MH+, 79/81Br).
References
[1] Patent: WO2015/73528, 2015, A1. Location in patent: Page/Page column 197
1H-Indole, 6-broMo-2-Methyl- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Indole, 6-broMo-2-Methyl- Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 1H-Indole, 6-broMo-2-Methyl- manufacturers
- Product
- 6-Bromo-2-methyl-1H-indole 6127-19-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2020-01-10
- Product
- 6-Bromo-2-methyl-1H-indole 6127-19-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-09