1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester

Product Name: 1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester
CAS No.: 912444-90-7
Chemical Name: 1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester
Synonyms: 1-Boc-azepane-4-carboxylic acid ethyl ester;1-tert-Butyl 4-ethyl azepane-1,4-dicarboxylate;1-O-tert-butyl 4-O-ethyl azepane-1,4-dicarboxylate;1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester;1H-Azepine-1,4-dicarboxylic acid, hexahydro-, 1-(1,1-diMethylethyl) 4-ethyl ester
CBNumber: CB82642819
Molecular Formula: C14H25NO4
Formula Weight: 271.35
MOL File: 912444-90-7.mol

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1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester Property

Boiling point:: 341.6±35.0 °C(Predicted)
Density: 1.057±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -2.04±0.40(Predicted)
Appearance: Colorless to light yellow Liquid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0047281
Product name: 1-(tert-Butyl)4-ethylazepane-1,4-dicarboxylate
Packaging: 1g
Price: $677
Updated: 2021/12/16

ChemScene

Product number: CS-0047281
Product name: 1-(tert-Butyl)4-ethylazepane-1,4-dicarboxylate
Packaging: 5g
Price: $2030
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0387430
Product name: 1-TERT-BUTYL 4-ETHYL AZEPANE-1,4-DICARBOXYLATE
Purity: 95.00%
Packaging: 5MG
Price: $504.39
Updated: 2021/12/16

AK Scientific

Product number: X6734
Product name: 1-tert-Butyl4-ethylazepane-1,4-dicarboxylate
Packaging: 1g
Price: $644
Updated: 2021/12/16

Abosyn

Product number: 10-3426
Product name: 1-tert-butyl4-ethylazepane-1,4-dicarboxylate
Purity: 95%-98%
Packaging: 1g
Price: $650
Updated: 2021/12/16

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1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester Chemical Properties,Usage,Production

Synthesis

912444-89-4

912444-90-7

General procedure for the synthesis of ethyl 1-azepane-N-Boc-4-carboxylate from 1-tert-butyl 4-ethyl 1H-azepine-1,4-dicarboxylate from 2,3,6,7-tetrahydro-1H-azepine-1,4-dicarboxylic acid: 1-tert-butyl 4-ethyl azepine-1,4-dicarboxylate (0.54 g, 2.0 mmol) was dissolved in 20 ml of methanol, 10% Pd/C (50 mg) was added , and the reaction was carried out overnight under hydrogen atmosphere. After completion of the reaction, the solid catalyst was removed by filtration and the filtrate was concentrated. The resulting residue was purified by fast column chromatography (eluent: hexane solution of 20% ethyl acetate) to afford the target product ethyl 1-azepane-N-Boc-4-carboxylate (310 mg, 55% yield). The mass spectrum (DCI/NH3) showed m/z 272 (M+H)+.

References

[1] Patent: US2006/229289, 2006, A1. Location in patent: Page/Page column 22-23

1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester Suppliers

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912444-90-7, 1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl esterRelated Search:

1H-Azepine-1,4-dicarboxylic acid, hexahydro-, 1-(1,1-diMethylethyl) 4-ethyl ester

1-tert-Butyl 4-ethyl azepane-1,4-dicarboxylate

1-Boc-azepane-4-carboxylic acid ethyl ester

1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester

1-O-tert-butyl 4-O-ethyl azepane-1,4-dicarboxylate

912444-90-7