3-BroMobenzenesulfonyl fluoride
- Product Name
- 3-BroMobenzenesulfonyl fluoride
- CAS No.
- 454-65-9
- Chemical Name
- 3-BroMobenzenesulfonyl fluoride
- Synonyms
- 3-BroMobenzenesulfonyl fluoride;benzenesulfonyl fluoride, 3-bromo-;3-Bromobenzene-1-sulfonyl fluoride
- CBNumber
- CB82642970
- Molecular Formula
- C6H4BrFO2S
- Formula Weight
- 239.06
- MOL File
- 454-65-9.mol
3-BroMobenzenesulfonyl fluoride Property
- Boiling point:
- 122 °C(Press: 23 Torr)
- Density
- 1.7355 at 25 °C
- refractive index
- n/D 1.5392
- Flash point:
- >110°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- liquid
- Appearance
- Colorless to light yellow Liquid
Safety
- RIDADR
- UN 3265 8 / PGII
- WGK Germany
- 3
- HS Code
- 2904990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- ALD00212
- Product name
- 3-Bromobenzenesulfonyl fluoride
- Purity
- 95% (GC)
- Packaging
- 1g
- Price
- $96.5
- Updated
- 2025/07/31
- Product number
- B682648
- Product name
- 3-Bromobenzenesulfonyl fluoride
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- B682648
- Product name
- 3-Bromobenzenesulfonyl fluoride
- Packaging
- 1g
- Price
- $210
- Updated
- 2021/12/16
- Product number
- 194105
- Product name
- 3-Bromobenzenesulfonyl fluoride
- Purity
- 95%
- Packaging
- 1g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- V6027
- Product name
- 3-Bromobenzenesulfonyl fluoride
- Packaging
- 1g
- Price
- $177
- Updated
- 2021/12/16
3-BroMobenzenesulfonyl fluoride Chemical Properties,Usage,Production
Uses
Sulfonyl fluoride motif can be used as a connector for the assembly of -SO2- linked small molecules with proteins or nucleic acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and phosphate groups as linkers.
reaction suitability
reaction type: click chemistry
Synthesis
2905-24-0
454-65-9
The general procedure for the synthesis of the target compound (CAS: 454-65-9) from 3-bromobenzenesulfonyl chloride was as follows: to a stirred solution of 3-bromobenzenesulfonyl chloride (5 g, 0.0196 mol) in acetonitrile (20 ml) was added potassium fluoride (2.27 g, 0.0391 mol) and 18-crown-6 ether (0.08 g) sequentially and the reaction mixture was stirred at room temperature for for 18 hours. After completion of the reaction, the reaction mixture was washed with water (60 ml) and subsequently extracted with ethyl acetate (3 x 80 ml). The organic extracts were combined and dried with anhydrous sodium sulfate (Na2SO4). Finally, the solvent was evaporated under reduced pressure to give a yellow oily product (3.79 g, 81% yield). The 1H NMR (CDCl3) data of the product were as follows: δ 7.55 (1H, t), 7.92 (1H, d), 7.95 (1H, d), 8.14 (1H, s).
References
[1] Patent: WO2004/80986, 2004, A1. Location in patent: Page 8
[2] Australian Journal of Chemistry, 1953, vol. 6, p. 318
3-BroMobenzenesulfonyl fluoride Preparation Products And Raw materials
Raw materials
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View Lastest Price from 3-BroMobenzenesulfonyl fluoride manufacturers
- Product
- 3-BroMobenzenesulfonyl fluoride 454-65-9
- Price
- US $20.00-7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-08-06