ChemicalBook > CAS DataBase List > spiro<3.3>heptane-3-carboxylic acid

spiro<3.3>heptane-3-carboxylic acid

Uses

Product Name: spiro<3.3>heptane-3-carboxylic acid
CAS No.: 28114-87-6
Chemical Name: spiro<3.3>heptane-3-carboxylic acid
Synonyms: 3.3>spiro<heptane-3-carboxylic acid;spiro<3.3>heptane-3-carboxylic acid;Spiro[3.3]heptane-2-carboxylic acid - S11733;Spiro[3.3]heptane-2-carboxylic acid (7CI, 8CI, 9CI, ACI)
CBNumber: CB82655343
Molecular Formula: C8H12O2
Formula Weight: 140.18
MOL File: 28114-87-6.mol

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spiro<3.3>heptane-3-carboxylic acid Property

Melting point:: 25 °C
Boiling point:: 256.8±8.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: liquid
pka: 4.77±0.20(Predicted)
color: Colourless
InChI: InChI=1S/C8H12O2/c9-7(10)6-4-8(5-6)2-1-3-8/h6H,1-5H2,(H,9,10)
InChIKey: FUQHLUSGMOSPRQ-UHFFFAOYSA-N
SMILES: C1C2(CCC2)CC1C(O)=O

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Safety

HS Code: 2916200090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: S682525
Product name: Spiro[3.3]heptane-2-carboxylicacid
Packaging: 25mg
Price: $45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM1052105
Product name: SPIRO[3.3]HEPTANE-2-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $452.05
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2221-1-28
Product name: Spiro[3.3]heptane-2-carboxylic acid
Packaging: 1g
Price: $525
Updated: 2021/12/16

Matrix Scientific

Product number: 113256
Product name: Spiro[3.3]heptane-2-carboxylic acid
Packaging: 1g
Price: $851
Updated: 2021/12/16

AK Scientific

Product number: 4504AJ
Product name: Spiro[3.3]heptane-2-carboxylicacid
Packaging: 5g
Price: $1451
Updated: 2021/12/16

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spiro<3.3>heptane-3-carboxylic acid Chemical Properties,Usage,Production

Uses

Spiro[3.3]heptane-2-carboxylic acid is a carboxylic acid derivative that can be used as a pharmaceutical intermediate.

Synthesis

64775-97-9

28114-87-6

The general procedure for the synthesis of spiro[3.3]heptane-2,2-dicarboxylic acid from spiro[3.3]heptane-2,2-dicarboxylic acid was as follows: spiro[3.3]heptane-2,2-dicarboxylic acid (1.737 g, 9.43 mmol) was dissolved in pyridine (20 mL) and the reaction was heated at 115 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated to dryness in a rotary evaporator. The resulting residue was treated with 6 M aqueous hydrochloric acid and subsequently extracted with dichloromethane (3 x 20 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated to dryness to afford spiro[3.3]heptane-2-carboxylic acid (1.21 g, 92% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 11.98 (s, 1H), 2.85 (m, 1H), 2.15-2.03 (m, 4H), 1.96 (t, J = 7.3 Hz, 2H), 1.84 (t, J = 7.3 Hz, 2H), 1.76-1.70 (m, 2H).

References

[1] Patent: US2014/275080, 2014, A1. Location in patent: Paragraph 0368
[2] Justus Liebigs Annalen der Chemie, 1961, vol. 648, p. 36 - 50

spiro<3.3>heptane-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from spiro<3.3>heptane-3-carboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Spiro[3.3]heptane-2-carboxylic acid 28114-87-6
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-05

Career Henan Chemical Co

Product: spiro<3.3>heptane-3-carboxylic acid 28114-87-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-07

28114-87-6, spiro<3.3>heptane-3-carboxylic acidRelated Search:

Spiro[3.3]Heptan-2-ylmethanol SPIRO[5.5]UNDECANE-2,4-DIONE Spiro[2.3]hexane-5-carboxylic acid, methyl ester SPIRO[4.5]DECANE-7,9-DIONE Methyl-spiro[2.3]hex-5-yl-amine SPIRO[2.3]HEXANE-5-CARBOXYLIC ACID spiro[2.5]octan-5,7-dione SPIRO[3.5]NONANE-6,8-DIONE 2-AMINOSPIRO[3.3]HEPTANE Spiro[2.3]hex-5-ylamine spiro[3.3]heptan-2-amine hydrochloride Spiro[3.5]nonan-7-ol Spiro[2.5]octane-6-carboxylic acid SPIRO[2.2]PENTANE-1-CARBOXYLIC ACID Spiro[2.5]octane-4,6-dione spiro[3.5]nonan-2-one Spiro[3.3]?heptane-?2,?2-?dicarboxylic acid, 2,?2-?bis(1-?methylethyl) ester spiro[2.4]heptan-7-one

spiro<3.3>heptane-3-carboxylic acid

Spiro[3.3]heptane-2-carboxylic acid - S11733

Spiro[3.3]heptane-2-carboxylic acid (7CI, 8CI, 9CI, ACI)

3.3&gt

heptane-3-carboxylic acid

spiro&lt

28114-87-6

28114-87-7