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2-BroMo-4-Methyl-1-nitro-benzene

Product Name
2-BroMo-4-Methyl-1-nitro-benzene
CAS No.
40385-54-4
Chemical Name
2-BroMo-4-Methyl-1-nitro-benzene
Synonyms
Benzene, 2-bromo-4-methyl-1-nitro-;2-bromo-4-methyl-1-nitro-benzene - [B86692]
CBNumber
CB82657327
Molecular Formula
C7H6BrNO2
Formula Weight
216.03
MOL File
40385-54-4.mol
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2-BroMo-4-Methyl-1-nitro-benzene Property

Melting point:
37.8°C
Boiling point:
269°C (rough estimate)
Density 
1.6841 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
Sealed in dry,Room Temperature
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B750165
Product name
3-Bromo-4-nitrotoluene
Packaging
2.5g
Price
$140
Updated
2021/12/16
TRC
Product number
B750165
Product name
3-Bromo-4-nitrotoluene
Packaging
5g
Price
$250
Updated
2021/12/16
TRC
Product number
B750165
Product name
3-Bromo-4-nitrotoluene
Packaging
10g
Price
$415
Updated
2021/12/16
SynQuest Laboratories
Product number
4754-9-04
Product name
2-Bromo-4-methyl-1-nitrobenzene
Packaging
25g
Price
$450
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0065969
Product name
2-BROMO-4-METHYL-1-NITROBENZENE
Purity
95.00%
Packaging
5MG
Price
$497.63
Updated
2021/12/16
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2-BroMo-4-Methyl-1-nitro-benzene Chemical Properties,Usage,Production

Uses

3-Bromo-4-nitrotoluene is a compound involved in the synthesis of novel phenylalanine-based amino acids as kainate receptor ligands.

Synthesis

583-68-6

40385-54-4

General procedure for the synthesis of 2-bromo-4-methyl-1-nitrobenzene from 2-bromo-4-methylaniline: 77% 3-chloroperoxybenzoic acid (150 mmol, 33.62 g) was added to a solution of 2-bromo-4-methylaniline (30 mmol, 5.56 g) in toluene (100 mL), and the reaction mixture was heated and refluxed for 6 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered. The filtrate was washed sequentially with 10% sodium hydroxide solution (2 x 100 mL) and saturated saline (100 mL), and the organic phase was dried with anhydrous sodium sulfate. The solvent was removed by evaporation under reduced pressure and the resulting residue was purified by fast column chromatography.

References

[1] Journal of the American Chemical Society, 2005, vol. 127, # 13, p. 4609 - 4624
[2] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 22, p. 5568 - 5572
[3] Collection of Czechoslovak Chemical Communications, 1967, vol. 32, # 1, p. 382 - 397
[4] Journal of medicinal chemistry, 1971, vol. 14, # 11, p. 1113 - 1115
[5] Tetrahedron Letters, 1992, vol. 33, # 33, p. 4799 - 4802

2-BroMo-4-Methyl-1-nitro-benzene Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BroMo-4-Methyl-1-nitro-benzene Suppliers

Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
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sales@harvest-chem.com
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China
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2816
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64
Beijing Eternalchem Co,. Ltd.
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010-59484199 18611897322
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Wuhan ariel chemical Co., LTD.
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18986259541
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Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd.
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Bide Pharmatech Ltd.
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ChongQing Purel Bio-Pharmaceutical Technology Co., Ltd.
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Changzhou Anxuan Chemical, Co., Ltd.
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NovoChemy Ltd.
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
Country
China
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71826
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View Lastest Price from 2-BroMo-4-Methyl-1-nitro-benzene manufacturers

Career Henan Chemical Co
Product
2-BroMo-4-Methyl-1-nitro-benzene 40385-54-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-23

40385-54-4, 2-BroMo-4-Methyl-1-nitro-benzeneRelated Search:


  • Benzene, 2-bromo-4-methyl-1-nitro-
  • 2-bromo-4-methyl-1-nitro-benzene - [B86692]
  • 40385-54-4