ChemicalBook > CAS DataBase List > L 2-401

L 2-401

Product Name
L 2-401
CAS No.
883050-24-6
Chemical Name
L 2-401
Synonyms
CS-563;L 2-401;CCG 50014;CCG50014;CCG 50014;CCG-50014 >=98% (HPLC);4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione;4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione;1,2,4-Thiadiazolidine-3,5-dione, 4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-;Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,inhibit,CCG50014,Inhibitor
CBNumber
CB82657938
Molecular Formula
C16H13FN2O2S
Formula Weight
316.35
MOL File
883050-24-6.mol
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L 2-401 Property

Density 
1.398±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
solubility 
DMSO: soluble5mg/mL, clear (warmed)
form 
powder
color 
white to beige
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0908
Product name
CCG-50014
Purity
≥98% (HPLC)
Packaging
5mg
Price
$122
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0908
Product name
CCG-50014
Purity
≥98% (HPLC)
Packaging
25mg
Price
$382
Updated
2024/03/01
Cayman Chemical
Product number
10802
Product name
CCG-50014
Purity
≥98%
Packaging
1mg
Price
$27
Updated
2024/03/01
Cayman Chemical
Product number
10802
Product name
CCG-50014
Purity
≥98%
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
10802
Product name
CCG-50014
Purity
≥98%
Packaging
10mg
Price
$146
Updated
2024/03/01
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L 2-401 Chemical Properties,Usage,Production

Description

CCG-50014 is an inhibitor of regulator of G protein signaling 4 (RGS4) (IC50 = 30 nM) and is > 20-fold selective for RGS4 over other RGS proteins. RGS proteins bind to the Gα subunits of activated heterotrimeric G proteins and accelerate the rate of GTP hydrolysis, acting as GTPase-activating proteins. CCG-50014 irreversibly binds and destabilizes RGS4 with no effect on Gα0, while blocking GTPase activity and Gα0-dependent translocation of RGS4 to the membrane.

L 2-401 Preparation Products And Raw materials

Raw materials

Preparation Products

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L 2-401 Suppliers

China 62 The Netherlands 1 United Kingdom 1 United States 13 Global 77
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883050-24-6, L 2-401Related Search:


  • 4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione
  • CCG 50014
  • L 2-401
  • 1,2,4-Thiadiazolidine-3,5-dione, 4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-
  • 4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione
  • CCG50014;CCG 50014
  • CS-563
  • CCG-50014 >=98% (HPLC)
  • Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,inhibit,CCG50014,Inhibitor
  • 883050-24-6
  • Inhibitors