ChemicalBook > CAS DataBase List > 2-(BroMoMethyl)-6-fluoropyridine
2-(BroMoMethyl)-6-fluoropyridine
- Product Name
- 2-(BroMoMethyl)-6-fluoropyridine
- CAS No.
- 100202-78-6
- Chemical Name
- 2-(BroMoMethyl)-6-fluoropyridine
- Synonyms
- -6-fluoropyridine;6-(bromomethyl)-2-fluoropyridine;2-(BroMoMethyl)-6-fluoropyridine;Pyridine, 2-(bromomethyl)-6-fluoro-
- CBNumber
- CB82660811
- Molecular Formula
- C6H5BrFN
- Formula Weight
- 190.01
- MOL File
- 100202-78-6.mol
More
Less
2-(BroMoMethyl)-6-fluoropyridine Property
- Boiling point:
- 208.8±25.0 °C(Predicted)
- Density
- 1.632±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -2.22±0.12(Predicted)
- form
- liquid
- color
- Colourless to light yellow
More
Less
Safety
- HS Code
- 2933399990
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- B679430
- Product name
- 2-(Bromomethyl)-6-fluoropyridine
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB105175
- Product name
- 2-(bromomethyl)-6-fluoropyridine
- Packaging
- 100mg
- Price
- $85
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC56100
- Product name
- 2-(Bromomethyl)-6-fluoropyridine
- Packaging
- 250mg
- Price
- $116
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB105175
- Product name
- 2-(bromomethyl)-6-fluoropyridine
- Packaging
- 250mg
- Price
- $170
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB105175
- Product name
- 2-(bromomethyl)-6-fluoropyridine
- Packaging
- 50mg
- Price
- $50
- Updated
- 2021/12/16
More
Less
2-(BroMoMethyl)-6-fluoropyridine Chemical Properties,Usage,Production
Synthesis
407-22-7
100202-78-6
The general procedure for the synthesis of 2-(bromomethyl)-6-fluoropyridine from 2-fluoro-6-methylpyridine was as follows: 2-fluoro-6-methylpyridine (4.32 g, 38.9 mmol), N-bromosuccinimide (NBS, 6 g, 33.7 mmol) and azobisisobutyronitrile (AIBN, 0.56 g, 3.4 mmol) were mixed in carbon tetrachloride (CCl4 , 50 mL). The reaction mixture was heated to 80°C and kept stirring for 3 hours. After completion of the reaction, it was cooled to room temperature and insoluble impurities were removed by filtration through diatomaceous earth. The filtrate was concentrated under reduced pressure and purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (9:1, v/v). The target fraction was collected and concentrated to give 4 g of the yellow oily product 2-(bromomethyl)-6-fluoropyridine in 54% yield.
References
[1] Patent: CN106749268, 2017, A. Location in patent: Paragraph 0729; 0730
[2] Patent: WO2007/2181, 2007, A2. Location in patent: Page/Page column 148-149
[3] Patent: US2010/69404, 2010, A1. Location in patent: Page/Page column 14
[4] Chemistry - A European Journal, 2016, vol. 22, # 5, p. 1602 - 1607
2-(BroMoMethyl)-6-fluoropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
2-(BroMoMethyl)-6-fluoropyridine Suppliers
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
- ProdList
- 9637
- Advantage
- 58
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 028-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
- ProdList
- 7218
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 027-59362599 18674037007
- Fax
- 027-84802889
- zhuoxingwc@163.com
- Country
- China
- ProdList
- 950
- Advantage
- 58
- Tel
- 025-66113011 13155353615
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15394
- Advantage
- 58
- Tel
- 400-8210725 400821072
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25000
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- +86-188369842 +86-15618151133
- Fax
- QQ188369842
- 188369842@qq.com
- Country
- China
- ProdList
- 1959
- Advantage
- 58
- Tel
- +86-27-8746-5837 +8619945049750
- Fax
- 86 27 87772287
- info@finetechnology-ind.com
- Country
- China
- ProdList
- 9629
- Advantage
- 58
- Tel
- 0086-19817745290; +8619817745290
- bd@blocksynth.com
- Country
- China
- ProdList
- 5661
- Advantage
- 58
- Tel
- 021-021-54321516 17717324060
- 2719672468@qq.com
- Country
- China
- ProdList
- 2032
- Advantage
- 58
- Tel
- 18151111370
- 1046215251@qq.com
- Country
- China
- ProdList
- 5999
- Advantage
- 58
- Tel
- 0371-0371-55135753 18003832934
- Fax
- QQ：2853979818
- 2853979818@qq.com
- Country
- China
- ProdList
- 9991
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing1@energy-chemical.com
- Country
- China
- ProdList
- 44894
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
- Tel
- 15870833005
- 2232044025@qq.com
- Country
- China
- ProdList
- 8206
- Advantage
- 58
- Tel
- 15952404857
- sales@dolanpharm.com
- Country
- China
- ProdList
- 2920
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39665
- Advantage
- 58
- Tel
- 0574-27891269 18667892864
- frank.xiaodong@chemriotech.com
- Country
- China
- ProdList
- 3883
- Advantage
- 58
- Tel
- 15387063101
- 2881924050@qq.com
- Country
- China
- ProdList
- 9957
- Advantage
- 58
- Tel
- 15652467323
- sales@inno-chem.com.cn
- Country
- China
- ProdList
- 8293
- Advantage
- 58
- Tel
- +86(21)5895 0110 19945755304
- sales@chemany.com
- Country
- China
- ProdList
- 9984
- Advantage
- 58
- Tel
- 029-029-63373950 17392216152
- 1050@dideu.com
- Country
- China
- ProdList
- 9998
- Advantage
- 58
- Tel
- 13771737464
- sales@dolanchem.com
- Country
- China
- ProdList
- 2172
- Advantage
- 58
- Tel
- 18621169109
- market03@meryer.com
- Country
- China
- ProdList
- 27987
- Advantage
- 58
- Tel
- 16696119288
- 779113375@qq.com
- Country
- China
- ProdList
- 7236
- Advantage
- 58
- Tel
- 13820634634 18622687818
- 405423999@qq.com
- Country
- China
- ProdList
- 3298
- Advantage
- 58
- Tel
- 021-57520305 13795461237
- zhuruyan@jskchem.com
- Country
- China
- ProdList
- 49234
- Advantage
- 58
- Tel
- 021-68080707 18079794756
- soloman.lee@chemlin.com.cn
- Country
- China
- ProdList
- 8481
- Advantage
- 58
- Tel
- 400-0628126 15697567703
- sales-team@aobchem.com.cn
- Country
- China
- ProdList
- 49999
- Advantage
- 58
- Tel
- 021-54306202 18917919676
- info@hanhongsci.com
- Country
- China
- ProdList
- 29995
- Advantage
- 58
- Tel
- 19817745290
- bd@blocksynth.com
- Country
- China
- ProdList
- 5870
- Advantage
- 58
- Tel
- 021-34045219 13062664914
- huji@zunlijia.com
- Country
- China
- ProdList
- 10027
- Advantage
- 58
- Tel
- 18600731423
- jason_gao@yl-pharminblock.com
- Country
- China
- ProdList
- 1952
- Advantage
- 58
- Tel
- 15866847540
- dengyt2000@163.com
- Country
- China
- ProdList
- 4100
- Advantage
- 58
- Tel
- 17316404525 17316404525
- 209533805@qq.com
- Country
- China
- ProdList
- 9763
- Advantage
- 58
- Tel
- 17717618050
- zllg@gh-reagent.com
- Country
- China
- ProdList
- 10420
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58
- Tel
- +8615303909093
- sales@compound-net.com
- Country
- China
- ProdList
- 2914
- Advantage
- 58
- Tel
- +undefined18600731423
- jason_gao@yl-pharminblock.com
- Country
- China
- ProdList
- 1944
- Advantage
- 58
- Tel
- +86-571-87711850
- market18@leapchem.com
- Country
- China
- ProdList
- 43339
- Advantage
- 58
- Tel
- +86-25-58227606 +86-15305155328
- sales@dogechemical.com
- Country
- China
- ProdList
- 4128
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@zzsrm.com
- Country
- CHINA
- ProdList
- 6650
- Advantage
- 58
- Tel
- --
- Fax
- --
- Country
- China
- ProdList
- 6891
- Advantage
- 50