ChemicalBook > CAS DataBase List > 6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE

6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE

Product Name
6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE
CAS No.
769-27-7
Chemical Name
6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE
Synonyms
6-amino-2,4-dimethyL;6-amino-2,4-dimethylpyridine-3-carbonitrile;6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE;3-Pyridinecarbonitrile, 6-amino-2,4-dimethyl-
CBNumber
CB82665290
Molecular Formula
C8H9N3
Formula Weight
147.18
MOL File
769-27-7.mol
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6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE Property

Melting point:
230 °C
Boiling point:
314.5±42.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
4.30±0.48(Predicted)
Appearance
Off-white to yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S461237
Product name
6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$197
Updated
2026/03/19
Sigma-Aldrich
Product number
S461237
Product name
6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE
Purity
Aldrich
Packaging
250mg
Price
$179
Updated
2024/03/01
AK Scientific
Product number
1456BB
Product name
6-Amino-2,4-dimethylnicotinonitrile
Packaging
1g
Price
$168
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0126901
Product name
6-AMINO-2,4-DIMETHYLNICOTINONITRILE
Purity
95.00%
Packaging
1MG
Price
$597.89
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0126901
Product name
6-AMINO-2,4-DIMETHYLNICOTINONITRILE
Purity
95.00%
Packaging
10MG
Price
$631.85
Updated
2021/12/16
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6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE Chemical Properties,Usage,Production

Synthesis

557-21-1

885952-12-5

769-27-7

To a solution of 5-iodo-4,6-dimethylpyridin-2-amine (10 g, 40.3 mmol, 1.0 eq.) in N,N-dimethylformamide (DMF, 300 mL) was sequentially added zinc cyanide (Zn(CN)2, 14 g, 120.9 mmol, 3.0 eq.) and tetrakis(triphenylphosphine)palladium (Pd(PPh3)4, 4.65 g, 4.03 mmol, 0.1 equiv). The reaction mixture was stirred at 90 °C under nitrogen (N2) protection overnight. After completion of the reaction, extraction was carried out by adding ethyl acetate (EA) and water. The organic layer was separated and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol=100/1, v/v) to afford 6-amino-2,4-dimethyl-3-cyanopyridine (5 g, 84% yield) as a yellow solid.

References

[1] Patent: WO2017/1926, 2017, A2. Location in patent: Paragraph 00123

6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE Suppliers

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769-27-7, 6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILERelated Search:


  • 6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE
  • 6-amino-2,4-dimethylpyridine-3-carbonitrile
  • 6-amino-2,4-dimethyL
  • 3-Pyridinecarbonitrile, 6-amino-2,4-dimethyl-
  • 769-27-7