ChemicalBook > CAS DataBase List > KN92
KN92
- Product Name
- KN92
- CAS No.
- 176708-42-2
- Chemical Name
- KN92
- Synonyms
- K92;K 92;KN-92 free base;KN-92;KN 92;KN92;N-[2-[[[(E)-3-(4-CHLOROPHENYL)PROP-2-ENYL]-METHYLAMINO]METHYL]PHENYL]-4-METHOXYBENZENESULFONAMIDE;Benzenesulfonamide, N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-4-methoxy-
- CBNumber
- CB82666646
- Molecular Formula
- C24H25ClN2O3S
- Formula Weight
- 456.98
- MOL File
- 176708-42-2.mol
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KN92 Property
- Boiling point:
- 602.1±65.0 °C(Predicted)
- Density
- 1.282±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥ 15.1 mg/mL in DMSO, ≥ 24.2 mg/mL in EtOH with gentle warming
- form
- Solid
- pka
- 8.49±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ApexBio Technology
- Product number
- A3529
- Product name
- KN-92
- Packaging
- 5mg
- Price
- $246
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A3529
- Product name
- KN-92
- Packaging
- 10mg
- Price
- $339
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A3529
- Product name
- KN-92
- Packaging
- 50mg
- Price
- $986
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A3529
- Product name
- KN-92
- Packaging
- 200mg
- Price
- $2262
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN19064
- Product name
- KN-92
- Packaging
- 25mg
- Price
- $539
- Updated
- 2021/12/16
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KN92 Chemical Properties,Usage,Production
Uses
KN-92 is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor[1][2].
References
[1] Smyth JT, et al. Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism. J Biol Chem. 2002;277(38):35061-35070. DOI:10.1074/jbc.M202928200
[2] An P, et al. KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro. World J Gastroenterol. 2007;13(9):1445-1448. DOI:10.3748/wjg.v13.i9.1445
KN92 Preparation Products And Raw materials
Raw materials
Preparation Products
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