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KN92

Product Name
KN92
CAS No.
176708-42-2
Chemical Name
KN92
Synonyms
K92;K 92;KN-92 free base;KN-92;KN 92;KN92;N-[2-[[[(E)-3-(4-CHLOROPHENYL)PROP-2-ENYL]-METHYLAMINO]METHYL]PHENYL]-4-METHOXYBENZENESULFONAMIDE;Benzenesulfonamide, N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-4-methoxy-
CBNumber
CB82666646
Molecular Formula
C24H25ClN2O3S
Formula Weight
456.98
MOL File
176708-42-2.mol
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KN92 Property

Boiling point:
602.1±65.0 °C(Predicted)
Density 
1.282±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≥ 15.1 mg/mL in DMSO, ≥ 24.2 mg/mL in EtOH with gentle warming
form 
Solid
pka
8.49±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A3529
Product name
KN-92
Packaging
5mg
Price
$246
Updated
2021/12/16
ApexBio Technology
Product number
A3529
Product name
KN-92
Packaging
10mg
Price
$339
Updated
2021/12/16
ApexBio Technology
Product number
A3529
Product name
KN-92
Packaging
50mg
Price
$986
Updated
2021/12/16
ApexBio Technology
Product number
A3529
Product name
KN-92
Packaging
200mg
Price
$2262
Updated
2021/12/16
CSNpharm
Product number
CSN19064
Product name
KN-92
Packaging
25mg
Price
$539
Updated
2021/12/16
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KN92 Chemical Properties,Usage,Production

Uses

KN-92 is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor[1][2].

References

[1] Smyth JT, et al. Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism. J Biol Chem. 2002;277(38):35061-35070. DOI:10.1074/jbc.M202928200
[2] An P, et al. KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro. World J Gastroenterol. 2007;13(9):1445-1448. DOI:10.3748/wjg.v13.i9.1445

KN92 Preparation Products And Raw materials

Raw materials

Preparation Products

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KN92 Suppliers

Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 13167063860
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021-50323701
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anhua.mao@aladdin-e.com
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China
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SPIRO PHARMA
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18620099427
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176708-42-2, KN92Related Search:


  • N-[2-[[[(E)-3-(4-CHLOROPHENYL)PROP-2-ENYL]-METHYLAMINO]METHYL]PHENYL]-4-METHOXYBENZENESULFONAMIDE
  • KN-92;KN 92;KN92
  • Benzenesulfonamide, N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-4-methoxy-
  • K 92
  • K92
  • KN-92 free base
  • 176708-42-2