ChemicalBook > CAS DataBase List > Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-

Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-

Product Name
Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-
CAS No.
1312782-34-5
Chemical Name
Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-
Synonyms
AA26-8;AA26-9;AA26-9, 10 mM in DMSO;Pyrrolidin-1-yl-[1,2,3]triazol-1-yl-methanone;Pyrrolidin-1-yl(1H-1,2,3-triazol-1-yl)methanone;Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-;peptidases,thioesterases,AA26-9,Phospholipase,AA269,serine,esterases,AA-26-9,AA26 9,Inhibitor,lipases,amidases,inhibit,cell
CBNumber
CB82667906
Molecular Formula
C7H10N4O
Formula Weight
166.18
MOL File
1312782-34-5.mol
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Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Property

Boiling point:
306.7±25.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO:100.0(Max Conc. mg/mL);601.76(Max Conc. mM)
form 
A solid
pka
-0.71±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-6521
Product name
AA26-9
Purity
98.03%
Packaging
5mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-6521
Product name
AA26-9
Purity
98.03%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-6521
Product name
AA26-9
Purity
98.03%
Packaging
50mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-6521
Product name
AA26-9
Purity
98.03%
Packaging
100mg
Price
$850
Updated
2021/12/16
DC Chemicals
Product number
DC10165
Product name
AA26-9
Purity
>98%
Packaging
1g
Price
$1800
Updated
2021/12/16
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Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Chemical Properties,Usage,Production

Uses

AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. AA26-9 shows inhibitory activity against approximately 1/3 of the 40+ serine hydrolases detected in immortalized T cell lines [1][2].

References

[1] Adibekian A, et al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78. DOI:10.1038/nchembio.579
[2] Borne AL, et al. Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling. Curr Top Microbiol Immunol. 2019;420:175-210. DOI:10.1007/82_2018_124

Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- manufacturers

Career Henan Chemical Co
Product
Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- 1312782-34-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

1312782-34-5, Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-Related Search:


  • Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-
  • Pyrrolidin-1-yl-[1,2,3]triazol-1-yl-methanone
  • AA26-9
  • peptidases,thioesterases,AA26-9,Phospholipase,AA269,serine,esterases,AA-26-9,AA26 9,Inhibitor,lipases,amidases,inhibit,cell
  • AA26-8
  • Pyrrolidin-1-yl(1H-1,2,3-triazol-1-yl)methanone
  • AA26-9, 10 mM in DMSO
  • 1312782-34-5