Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-
- Product Name
- Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-
- CAS No.
- 1312782-34-5
- Chemical Name
- Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-
- Synonyms
- AA26-8;AA26-9;AA26-9, 10 mM in DMSO;Pyrrolidin-1-yl-[1,2,3]triazol-1-yl-methanone;Pyrrolidin-1-yl(1H-1,2,3-triazol-1-yl)methanone;Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-;peptidases,thioesterases,AA26-9,Phospholipase,AA269,serine,esterases,AA-26-9,AA26 9,Inhibitor,lipases,amidases,inhibit,cell
- CBNumber
- CB82667906
- Molecular Formula
- C7H10N4O
- Formula Weight
- 166.18
- MOL File
- 1312782-34-5.mol
Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Property
- Boiling point:
- 306.7±25.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO:100.0(Max Conc. mg/mL);601.76(Max Conc. mM)
- form
- A solid
- pka
- -0.71±0.70(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-6521
- Product name
- AA26-9
- Purity
- 98.03%
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- CS-6521
- Product name
- AA26-9
- Purity
- 98.03%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-6521
- Product name
- AA26-9
- Purity
- 98.03%
- Packaging
- 50mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- CS-6521
- Product name
- AA26-9
- Purity
- 98.03%
- Packaging
- 100mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- DC10165
- Product name
- AA26-9
- Purity
- >98%
- Packaging
- 1g
- Price
- $1800
- Updated
- 2021/12/16
Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Chemical Properties,Usage,Production
Uses
AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. AA26-9 shows inhibitory activity against approximately 1/3 of the 40+ serine hydrolases detected in immortalized T cell lines [1][2].
References
[1] Adibekian A, et al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78. DOI:10.1038/nchembio.579
[2] Borne AL, et al. Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling. Curr Top Microbiol Immunol. 2019;420:175-210. DOI:10.1007/82_2018_124
Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- manufacturers
- Product
- Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- 1312782-34-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2019-12-23