ChemicalBook > CAS DataBase List > AICAR (phosphate)
AICAR (phosphate)
- Product Name
- AICAR (phosphate)
- CAS No.
- 681006-28-0
- Chemical Name
- AICAR (phosphate)
- Synonyms
- AICAR (phosphate);Acadesine phosphate;AICAR phosphate, >98%;AICA Riboside phosphate);AICAR (Acadesine) phosphate;AICA-riboside monophosphate;AICAR phosphate (Acadesine phosphate;ACADESINE PHOSPHATE;AICA RIBOSIDE PHOSPHATE;5-Amino-1-ribosylimidazole-4-carboxamide phosphate
- CBNumber
- CB82677075
- Molecular Formula
- C9H17N4O9P
- Formula Weight
- 356.23
- MOL File
- 681006-28-0.mol
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AICAR (phosphate) Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ApexBio Technology
- Product number
- B1211
- Product name
- AICARphosphate
- Packaging
- 50mg
- Price
- $40
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B1211
- Product name
- AICARphosphate
- Packaging
- 200mg
- Price
- $120
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-1952
- Product name
- AICAR(phosphate)
- Purity
- 99.49%
- Packaging
- 500mg
- Price
- $336
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611683
- Product name
- AICAR phosphate
- Packaging
- 250mg
- Price
- $345.1
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B1211
- Product name
- AICARphosphate
- Packaging
- 1g
- Price
- $350
- Updated
- 2021/12/16
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AICAR (phosphate) Chemical Properties,Usage,Production
Biological Activity
aicar phosphate （acadesine）is an activator of ampk [1].aicar phosphate has been reported to induce apoptosis in a dose-dependent fashion and that the ec50 value is 380±60μm on the viability assay of b-cll cells. in addition, aicar phosphate has been revealed to induce caspase activation and cytochrome c release from mitochondria in b-cll cells. furthermore, aicar phosphate has shown that uptake and phosphorylation are required to induce apoptosis and activate ampk. apart from these, aicar phosphate (2-4 mm) has shown to only slightly affects the viability of t cells from b-cll patients, aicar phosphate (0.5 mm) has been noted to remarkedly reduces viability of b cells but not t cells [1].
References
[1] campàs c1, lopez jm, santidrián af, barragán m, bellosillo b, colomer d, gil j. acadesine activates ampk and induces apoptosis in b-cell chronic lymphocytic leukemia cells but not in t lymphocytes. blood. 2003 may 1;101(9):3674-80. epub 2003 jan 9.
AICAR (phosphate) Preparation Products And Raw materials
Raw materials
Preparation Products
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