ChemicalBook > CAS DataBase List > Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)-

Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)-

Product Name
Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)-
CAS No.
681282-72-4
Chemical Name
Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)-
Synonyms
Saxagliptin Impurity 19;Boc-3,5-dihydroxy-1-adamantyl-L-glycine;Saxagliptin Impurity 6 (Saxagliptin Impurity);(S)-2-((tert-butoxycarbonyl)amino)-2-(3,5-dihydroxyadamantan-1-yl)acetic acid;(2S)-2-((tert-butoxycarbonyl)amino)-2-((3R,5S)-3,5-dihydroxyadamantan-1-yl)acetic acid;(S)-2-((tert-butoxycarbonyl)amino)-2-((1r,3R,5S,7S)-3,5-dihydroxyadamantan-1-yl)acetic acid;(2S)-2-[(3R,5S)-3,5-dihydroxy-1-adamantyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid;Tricyclo[3.3.1.13,?7]?decane-?1-?acetic acid, α-?[[(1,?1-?dimethylethoxy)?carbonyl]?amino]?-?3,?5-?dihydroxy-?, (αS)?-
CBNumber
CB82677161
Molecular Formula
C17H27NO6
Formula Weight
341.4
MOL File
681282-72-4.mol
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Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)- Property

Boiling point:
534.7±35.0 °C(Predicted)
Density 
1.406±0.06 g/cm3(Predicted)
pka
3.93±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B648220
Product name
Boc-3,5-dihydroxy-1-adamantyl-L-glycine
Packaging
25mg
Price
$165
Updated
2021/12/16
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Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)- Chemical Properties,Usage,Production

Uses

Boc-3,5-dihydroxy-1-adamantyl-L-glycine is a reactant in the synthesis of Saxagliptin (S143500), a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)- Preparation Products And Raw materials

Raw materials

Preparation Products

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681282-72-4, Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)-Related Search:


  • (2S)-2-[(3R,5S)-3,5-dihydroxy-1-adamantyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid
  • (S)-2-((tert-butoxycarbonyl)amino)-2-(3,5-dihydroxyadamantan-1-yl)acetic acid
  • Saxagliptin Impurity 19
  • Boc-3,5-dihydroxy-1-adamantyl-L-glycine
  • (S)-2-((tert-butoxycarbonyl)amino)-2-((1r,3R,5S,7S)-3,5-dihydroxyadamantan-1-yl)acetic acid
  • (2S)-2-((tert-butoxycarbonyl)amino)-2-((3R,5S)-3,5-dihydroxyadamantan-1-yl)acetic acid
  • Saxagliptin Impurity 6 (Saxagliptin Impurity)
  • Tricyclo[3.3.1.13,?7]?decane-?1-?acetic acid, α-?[[(1,?1-?dimethylethoxy)?carbonyl]?amino]?-?3,?5-?dihydroxy-?, (αS)?-
  • 681282-72-4