1-(1-Methyl-1H-iMidazol-5-yl)ethanone
- Product Name
- 1-(1-Methyl-1H-iMidazol-5-yl)ethanone
- CAS No.
- 20970-50-7
- Chemical Name
- 1-(1-Methyl-1H-iMidazol-5-yl)ethanone
- Synonyms
- 5-Acetyl-1-methylimidazole;1-(3-methylimidazol-4-yl)ethanone;1-(1-Methyl-1H-iMidazol-5-yl)ethanone;Ethanone, 1-(1-methyl-1H-imidazol-5-yl)-
- CBNumber
- CB82677338
- Molecular Formula
- C6H8N2O
- Formula Weight
- 124.14
- MOL File
- 20970-50-7.mol
1-(1-Methyl-1H-iMidazol-5-yl)ethanone Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 4596AQ
- Product name
- 1-(3-methylimidazol-4-yl)ethanone
- Packaging
- 100mg
- Price
- $245.6
- Updated
- 2021/12/16
- Product number
- 4596AQ
- Product name
- 1-(3-methylimidazol-4-yl)ethanone
- Packaging
- 250mg
- Price
- $377.6
- Updated
- 2021/12/16
- Product number
- 4596AQ
- Product name
- 1-(3-methylimidazol-4-yl)ethanone
- Packaging
- 1g
- Price
- $706.4
- Updated
- 2021/12/16
- Product number
- CHM0371342
- Product name
- 1-(1-METHYL-1H-IMIDAZOL-5-YL)ETHANONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.86
- Updated
- 2021/12/16
- Product number
- 61-10383
- Product name
- 1-(1-Methyl-1H-imidazol-5-yl)ethanone
- Purity
- 95-98%
- Packaging
- 1g
- Price
- $522
- Updated
- 2021/12/16
1-(1-Methyl-1H-iMidazol-5-yl)ethanone Chemical Properties,Usage,Production
Synthesis
592554-79-5
75-16-1
20970-50-7
General procedure for the synthesis of 1-(1-methyl-1H-imidazol-5-yl)ethanone from the compound (CAS: 592554-79-5) and methylmagnesium bromide: First, the crude product (882) (14.2 mmol) was dissolved in tetrahydrofuran (THF) (100 mL). Methylmagnesium bromide (3 M solution in ether) (22.2 mL) was slowly added under cooling conditions in an ice bath, the titration was controlled to be completed within 10 min and the reaction was carried out under nitrogen (N2) protection. Subsequently, the reaction mixture was warmed up to 40 °C and stirred continuously for 4 h or until the reaction was complete. After completion of the reaction, it was again cooled in an ice bath and the reaction was quenched by slow addition of saturated ammonium chloride (NH4Cl) solution. Initial extraction was carried out with ethyl acetate followed by three extractions with dichloromethane (CH2Cl2). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and the solvent evaporated. Finally, the product was stored under vacuum to afford crystalline 1-(1-methyl-1H-imidazol-5-yl)ethanone (883) (1.78 g, 74% yield).
References
[1] Patent: US2004/122018, 2004, A1. Location in patent: Page 349
1-(1-Methyl-1H-iMidazol-5-yl)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
1-(1-Methyl-1H-iMidazol-5-yl)ethanone Suppliers
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