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HEPTANOYL THIO-PC

Product Name
HEPTANOYL THIO-PC
Chemical Name
HEPTANOYL THIO-PC
Synonyms
HEPTANOYL THIO-PC
CBNumber
CB8269696
Molecular Formula
C31H64NO6PS
Formula Weight
609.88
MOL File
Mol file
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HEPTANOYL THIO-PC Property

solubility 
DMF: 10 mg/ml
DMSO: 2 mg/ml
Ethanol: 30 mg/ml
Ethanol: PBS (pH 7.2)(1:8): .5 mg/ml
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10006809
Product name
Heptanoyl thio-PC
Purity
≥98%
Packaging
5mg
Price
$151
Updated
2024/03/01
Cayman Chemical
Product number
10006809
Product name
Heptanoyl thio-PC
Purity
≥98%
Packaging
10mg
Price
$286
Updated
2024/03/01
Cayman Chemical
Product number
10006809
Product name
Heptanoyl thio-PC
Purity
≥98%
Packaging
25mg
Price
$673
Updated
2024/03/01
Cayman Chemical
Product number
10006809
Product name
Heptanoyl thio-PC
Purity
≥98%
Packaging
50mg
Price
$1195
Updated
2024/03/01
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HEPTANOYL THIO-PC Chemical Properties,Usage,Production

Description

Thioester analogs of glycerophospholipids, in combination with Ellman’s reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Diheptanoyl thio-PC is a commonly-used colorimetric substrate for all PLA2s, with the exception of cPLA2 and platelet-activating factor acetylhydrolase (PAF-AH). Thioester analogs of glycerophospholipids, in combination with Ellman’s reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Diheptanoyl thio-PC is a commonly-used colorimetric substrate for all PLA2s, with the exception of cPLA2 and platelet-activating factor acetylhydrolase (PAF-AH). Heptanoyl thio-PC is an analog of diheptanoyl thio-PC that contains an ether-linked saturated C16 moiety at the sn-1 position rather than a heptanoyl thiol ester. Porcine pancreatic and bee venom sPLA2 enzymes exhibit 10-13 fold less activity when assayed with heptanoyl thio-PC compared to diheptanoyl thio-PC. This decrease in activity has not been thoroughly investigated.

References

[1] H S HENDRICKSON  R H D  E K Hendrickson. Chiral synthesis of a dithiolester analog of phosphatidylcholine as a substrate for the assay of phospholipase A2.[J]. Journal of Lipid Research, 1983, 24 11: 1532-1537.
[2] LAURE J. REYNOLDS  Edward A D  Lori L Hughes. Analysis of human synovial fluid phospholipase A2 on short chain phosphatidylcholine-mixed micelles: Development of a spectrophotometric assay suitable for a microtiterplate reader[J]. Analytical biochemistry, 1992, 204 1: Pages 190-197. DOI: 10.1016/0003-2697(92)90160-9
[3] SUNDERLAND D, UZOIGWE G N. Personal Communication[J]. Communications in Africa, 1880–1939, 2018, 73 1: 0. DOI: 10.4324/9781351112277-85
[4] ROBERTS M F. Phospholipases: structural and functional motifs for working at an interface[J]. FASEB Journal, 1996, 10 10: 1159-1172. DOI: 10.1096/fasebj.10.10.8751718

HEPTANOYL THIO-PC Preparation Products And Raw materials

Raw materials

Preparation Products

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HEPTANOYL THIO-PC Suppliers

China 24 United States 2 Global 26
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Chongqing Boer Biotechnology Co., Ltd.
Tel
13251428727， 13368356747
Country
CHINA
ProdList
157
Advantage
58
Guangzhou Squirrel Biotechnology Co., Ltd.
Tel
17765276361
Country
CHINA
ProdList
109
Advantage
58
Aoki Biotechnology (Shenzhen) Co., Ltd.
Tel
18566777408
Country
CHINA
ProdList
156
Advantage
58
Shenzhen Science Biology Co., Ltd.
Tel
18617181553
Country
CHINA
ProdList
112
Advantage
58

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