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Afatinib IMpurity J

Product Name
Afatinib IMpurity J
CAS No.
1456696-14-2
Chemical Name
Afatinib IMpurity J
Synonyms
Afatinib B;Afatinib IMpurity J;Afatinib Impurity J HCl;(S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide;(2E)-4-(Dimethylamino)-N-{4-oxo-7-[(3S)-tetrahydro-3-furanyloxy]-1,4-dihydro-6-quinazolinyl}-2-butenamide;(2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;2-Butenamide, N-[3,4-dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-;(S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity);Afatinib impurity 8/(2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
CBNumber
CB82706586
Molecular Formula
C18H22N4O4
Formula Weight
358.39
MOL File
1456696-14-2.mol
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Afatinib IMpurity J Property

Density 
1.33±0.1 g/cm3(Predicted)
pka
11.89±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D495325
Product name
(2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
Packaging
1mg
Price
$165
Updated
2021/12/16
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Afatinib IMpurity J Chemical Properties,Usage,Production

Uses

(2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide, s an impurity of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

Afatinib IMpurity J Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Afatinib IMpurity J manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Afatinib impurity 57 1456696-14-2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-06-04
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Afatinib impurity J
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-06-05

1456696-14-2, Afatinib IMpurity JRelated Search:

Afatinib IMpurity H Alfatinib maleate Afatinib Impurity L (Afatinib N-Oxide) Afatinib Impurity I Afatinib Impurity K Afatinib Impurity 6 Afatinib IMpurity E 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Afatinib impurity 30 Afatinib Impurity 22 Afatinib Impurity 9 Afatinib-d6 Afatinib Impurity 74 Afatinib impurity 40 Afatinib impurity 33 Afatinib Impurity 14 Afatinib Impurity 18 Afatinib impurity 27

  • Afatinib IMpurity J
  • Afatinib Impurity J HCl
  • (2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
  • Afatinib impurity 8/(2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
  • (2E)-4-(Dimethylamino)-N-{4-oxo-7-[(3S)-tetrahydro-3-furanyloxy]-1,4-dihydro-6-quinazolinyl}-2-butenamide
  • 2-Butenamide, N-[3,4-dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
  • (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide
  • Afatinib B
  • (S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity)
  • 1456696-14-2