ChemicalBook > CAS DataBase List > 2-BroMo-4-fluoro-5-nitrobenzoic Acid

2-BroMo-4-fluoro-5-nitrobenzoic Acid

Product Name
2-BroMo-4-fluoro-5-nitrobenzoic Acid
CAS No.
1036389-83-9
Chemical Name
2-BroMo-4-fluoro-5-nitrobenzoic Acid
Synonyms
2-BroMo-4-fluoro-5-nitrobenzoic Acid;Benzoic acid, 2-bromo-4-fluoro-5-nitro-
CBNumber
CB82709451
Molecular Formula
C7H3BrFNO4
Formula Weight
264.01
MOL File
1036389-83-9.mol
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2-BroMo-4-fluoro-5-nitrobenzoic Acid Property

Boiling point:
379.8±42.0 °C(Predicted)
Density 
1.967±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.25±0.12(Predicted)
Appearance
Off-white to yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B685725
Product name
2-Bromo-4-fluoro-5-nitrobenzoicAcid
Packaging
10g
Price
$1320
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0068868
Product name
2-BROMO-4-FLUORO-5-NITROBENZOIC ACID
Purity
95.00%
Packaging
2.5G
Price
$1363.65
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0068868
Product name
2-BROMO-4-FLUORO-5-NITROBENZOIC ACID
Purity
95.00%
Packaging
1G
Price
$925.31
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0068868
Product name
2-BROMO-4-FLUORO-5-NITROBENZOIC ACID
Purity
95.00%
Packaging
5G
Price
$1759.28
Updated
2021/12/16
ChemScene
Product number
CS-W006521
Product name
2-Bromo-4-fluoro-5-nitrobenzoicacid
Packaging
250mg
Price
$51
Updated
2021/12/16
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2-BroMo-4-fluoro-5-nitrobenzoic Acid Chemical Properties,Usage,Production

Uses

2-Bromo-4-fluoro-5-nitrobenzoic Acid, is a halogenated derivative of benzoic acid. It can be used for the synthesis of various pharmaceutical compounds, such as amino acid derivatives acting as anticoagulants.

Synthesis

1006-41-3

1036389-83-9

Fuming nitric acid (4 mL, 45.60 mmol) was slowly added dropwise to a mixed solution containing 2-bromo-4-fluorobenzoic acid (10 g, 45.66 mmol) and concentrated sulfuric acid (34 mL) under cooling conditions in an ice bath. Upon completion of the reaction, the reaction mixture was poured into ice water and stirred vigorously for 1 hour. The precipitate was collected by filtration, washed with ice water and dried to give 10.40 g of white solid product. It was further washed with water and evaporated to dryness to finally obtain 2-bromo-4-fluoro-5-nitrobenzoic acid in white solid form in 86% yield.

References

[1] Patent: CN106146474, 2016, A. Location in patent: Paragraph 0097 - 0098
[2] Patent: US2018/291002, 2018, A1. Location in patent: Paragraph 0444; 0445
[3] Patent: WO2017/176812, 2017, A1. Location in patent: Paragraph 0451
[4] Patent: WO2008/79836, 2008, A2. Location in patent: Page/Page column 86-87

2-BroMo-4-fluoro-5-nitrobenzoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-BroMo-4-fluoro-5-nitrobenzoic Acid manufacturers

Career Henan Chemica Co
Product
2-BroMo-4-fluoro-5-nitrobenzoic Acid 1036389-83-9
Price
US $8.00/KG
Min. Order
1g
Purity
Min98% HPLC/gc
Supply Ability
g/kg/ton
Release date
2020-11-04

1036389-83-9, 2-BroMo-4-fluoro-5-nitrobenzoic AcidRelated Search:


  • 2-BroMo-4-fluoro-5-nitrobenzoic Acid
  • Benzoic acid, 2-bromo-4-fluoro-5-nitro-
  • 1036389-83-9