I-CBP112

Product Name: I-CBP112
CAS No.: 1640282-31-0
Chemical Name: I-CBP112
Synonyms: CS-2420;I-CBP112;I-CBP112, >98%;I-CBP112 hydrochloride;I-CBP112, 1640282-31-0;I-CBP112; I-CBP-112; I-CBP 112;I-CBP112,Inhibitor,HATs,I CBP112,inhibit,I-CBP-112,HAT,ICBP112,Epigenetic Reader Domain,Histone Acetyltransferase;1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methyl-3-piperidyl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one;1-Propanone, 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]-;1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one
CBNumber: CB82714666
Molecular Formula: C27H36N2O5
Formula Weight: 468.59
MOL File: 1640282-31-0.mol

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I-CBP112 Property

Boiling point:: 623.5±55.0 °C(Predicted)
Density: 1.129±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:63.0(Max Conc. mg/mL);134.44(Max Conc. mM)
Ethanol:94.0(Max Conc. mg/mL);200.6(Max Conc. mM)
Water:94.0(Max Conc. mg/mL);200.6(Max Conc. mM)
form: powder
pka: 9.07±0.10(Predicted)
color: white to beige

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Safety

RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1134
Product name: I-CBP112
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $197
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1134
Product name: I-CBP112
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $230.8
Updated: 2024/03/01

Tocris

Product number: 4891
Product name: I-CBP112
Purity: ≥98%(HPLC)
Packaging: 10
Price: $289
Updated: 2021/12/16

Tocris

Product number: 4891
Product name: I-CBP112
Purity: ≥98%(HPLC)
Packaging: 50
Price: $1195
Updated: 2021/12/16

TRC

Product number: I163883
Product name: I-CBP112
Packaging: 2.5mg
Price: $360
Updated: 2021/12/16

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I-CBP112 Chemical Properties,Usage,Production

Uses

I-CBP112 has been used in cell culture and sample preparation, to verify the acetylation of VPS34 (vacuolar protein sorting 34), by p300 at K29, K771 and K781 and to diminish synergistic gene expression.

Biochem/physiol Actions

I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors CREBBP (CBP) and EP300 (IC50 = 0.142 and 0.625 μM, respectively). I-CBP112 has little activity against other bromodomains at concentrations up to 1 mM. For full characterization details, please see I-CBP112 on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

storage

+4°C

I-CBP112 Preparation Products And Raw materials

Raw materials

Preparation Products

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I-CBP112 Suppliers

China 56 United Kingdom 1 United States 14 Global 71

Shanghai Boyle Chemical Co., Ltd.

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Email: sales@boylechem.com
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BOC Sciences

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MedChemexpress LLC

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Fax: 609-228-5909
Email: sales@medchemexpress.cn
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AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
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Email: info@adooq.com
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AdooQ Bioscience CHINA

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Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
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Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
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Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
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Shanghai Lollane Biological Technology Co.,Ltd.

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Fax: +86-21-52996696
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EMMX Biotechnology LLC

Tel: 888-539-0666
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Email: info@emmx.com
Country: United States
ProdList: 8449
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ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8012
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View Lastest Price from I-CBP112 manufacturers

Career Henan Chemica Co

Product: I-CBP112 1640282-31-0
Price: US $1.00/g
Min. Order: 1g
Purity: Min98% HPLC/GC
Supply Ability: g/kg/ton Coreychem-Nicole404
Release date: 2020-11-06

1640282-31-0, I-CBP112Related Search:

I-CBP112

1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one

I-CBP112, 1640282-31-0

I-CBP112 hydrochloride

I-CBP112, >98%

I-CBP112; I-CBP-112; I-CBP 112

CS-2420

1-Propanone, 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]-

I-CBP112,Inhibitor,HATs,I CBP112,inhibit,I-CBP-112,HAT,ICBP112,Epigenetic Reader Domain,Histone Acetyltransferase

1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methyl-3-piperidyl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one

1640282-31-0