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NIBR189

Product Name
NIBR189
CAS No.
1599432-08-2
Chemical Name
NIBR189
Synonyms
CS-1583;NIBR189;NIBR-189; NIBR 189;(E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one;(2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one;(2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-, (2E)-;Inhibitor,mice,small molecule,NIBR 189,autoimmune diseases,autoimmune,EBI2/GPR183,NIBR189,U937,NIBR-189,G protein,inhibit,migration
CBNumber
CB82715658
Molecular Formula
C21H21BrN2O3
Formula Weight
429.31
MOL File
1599432-08-2.mol
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NIBR189 Property

Boiling point:
639.7±55.0 °C(Predicted)
Density 
1.403±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at -20°C
solubility 
≥42.9 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form 
solid
pka
-0.86±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18792
Product name
NIBR189
Purity
≥95%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
18792
Product name
NIBR189
Purity
≥95%
Packaging
5mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
18792
Product name
NIBR189
Purity
≥95%
Packaging
10mg
Price
$172
Updated
2024/03/01
Tocris
Product number
5203
Product name
NIBR189
Purity
≥99%(HPLC)
Packaging
10
Price
$193
Updated
2021/12/16
Tocris
Product number
5203
Product name
NIBR189
Purity
≥99%(HPLC)
Packaging
50
Price
$789
Updated
2021/12/16
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NIBR189 Chemical Properties,Usage,Production

Uses

(2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one recently known as NIBR 189, is a selective Epstein-barr virus-induced gene 2 (EBI-2) receptor antagonist, resulting in a modulation of immune responses related to auto-immune diseases.

Biological Activity

nibr189 is a small molecule antagonist of the epstein-barr virus-induced gene 2 (ebi2; gpr183) receptor with ic50 of 16 nm(binding) and 11 nm (functional).

storage

Store at +4°C

NIBR189 Preparation Products And Raw materials

Raw materials

Preparation Products

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NIBR189 Suppliers

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1599432-08-2, NIBR189Related Search:


  • NIBR189
  • (E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one
  • (2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one
  • CS-1583
  • NIBR-189; NIBR 189
  • (2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one
  • 2-Propen-1-one, 3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-, (2E)-
  • Inhibitor,mice,small molecule,NIBR 189,autoimmune diseases,autoimmune,EBI2/GPR183,NIBR189,U937,NIBR-189,G protein,inhibit,migration
  • 1599432-08-2
  • api