ChemicalBook > CAS DataBase List > Mutant IDH1-IN-1

Mutant IDH1-IN-1

Product Name: Mutant IDH1-IN-1
CAS No.: 1355326-21-4
Chemical Name: Mutant IDH1-IN-1
Synonyms: CS-1779;IDH1-IN-1;Mutant IDH1-IN-1;Mutant IDH1 inhibitor 1;Mutant IDH1-IN-1, 10 mM in DMSO;2-(2-(1H-Benzo[d]imidazol-1-yl)-N-(3-fluorophenyl)acetamido)-N-cyclohexyl-2-(o-tolyl)acetamide;Mutant IDH1IN1,Isocitrate Dehydrogenase (IDH),Inhibitor,inhibit,Mutant IDH-1-IN-1,Mutant IDH1 IN 1;2-[2-(1H-1,3-benzodiazol-1-yl)-N-(3-fluorophenyl)acetamido]-N-cyclohexyl-2-(2-methylphenyl)acetamide;N-[2-(Cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-1H-benzimidazole-1-acetamide;1H-Benzimidazole-1-acetamide, N-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-
CBNumber: CB82729518
Molecular Formula: C30H31FN4O2
Formula Weight: 498.59
MOL File: 1355326-21-4.mol

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Mutant IDH1-IN-1 Property

storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form: A crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18394
Product name: Mutant IDH1-IN-1
Purity: ≥98%
Packaging: 1mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 18394
Product name: Mutant IDH1-IN-1
Purity: ≥98%
Packaging: 5mg
Price: $234
Updated: 2024/03/01

Cayman Chemical

Product number: 18394
Product name: Mutant IDH1-IN-1
Purity: ≥98%
Packaging: 10mg
Price: $380
Updated: 2024/03/01

Cayman Chemical

Product number: 18394
Product name: Mutant IDH1-IN-1
Purity: ≥98%
Packaging: 50mg
Price: $1019
Updated: 2024/03/01

ChemScene

Product number: CS-3552
Product name: MutantIDH1-IN-1
Purity: 99.60%
Packaging: 100mg
Price: $1900
Updated: 2021/12/16

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Mutant IDH1-IN-1 Chemical Properties,Usage,Production

Uses

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.

IC 50

IDH1

References

[1] Deng G, et al. Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. J Biol Chem. 2015 Jan 9;290(2):762-74. DOI:10.1074/jbc.M114.608497

Mutant IDH1-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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1355326-21-4, Mutant IDH1-IN-1Related Search:

Mutant IDH1-IN-1

IDH1-IN-1

N-[2-(Cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-1H-benzimidazole-1-acetamide

CS-1779

Mutant IDH1 inhibitor 1

1H-Benzimidazole-1-acetamide, N-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-

Mutant IDH1IN1,Isocitrate Dehydrogenase (IDH),Inhibitor,inhibit,Mutant IDH-1-IN-1,Mutant IDH1 IN 1

2-(2-(1H-Benzo[d]imidazol-1-yl)-N-(3-fluorophenyl)acetamido)-N-cyclohexyl-2-(o-tolyl)acetamide

2-[2-(1H-1,3-benzodiazol-1-yl)-N-(3-fluorophenyl)acetamido]-N-cyclohexyl-2-(2-methylphenyl)acetamide

Mutant IDH1-IN-1, 10 mM in DMSO

1355326-21-4

C30H31FN4O2

Inhibitors