MV151
- Product Name
- MV151
- CAS No.
- 945611-88-1
- Chemical Name
- MV151
- Synonyms
- MV151
- CBNumber
- CB82731106
- Molecular Formula
- C59H91BF2N8O9S
- Formula Weight
- 1137.29
- MOL File
- 945611-88-1.mol
MV151 Chemical Properties,Usage,Production
Description
MV151 is a fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. MV151 specifically targets all active subunits of the proteasome and immunoproteasome in living cells, allowing for rapid and sensitive in-gel detection. The inhibition profile of a panel of commonly used proteasome inhibitors could be readily determined by MV151 labeling. Administration of MV151 to mice allowed for in vivo labeling of proteasomes, which correlated with inhibition of proteasomal degradation in the affected tissues. This probe can be used for many applications ranging from clinical profiling of proteasome activity, to biochemical analysis of subunit specificity of inhibitors, and to cell biological analysis of the proteasome function and dynamics in living cells.
MV151 Preparation Products And Raw materials
Raw materials
Preparation Products
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