5-AMinothiophene-2-carbonitrile

Product Name: 5-AMinothiophene-2-carbonitrile
CAS No.: 52532-63-5
Chemical Name: 5-AMinothiophene-2-carbonitrile
Synonyms: 2-Amino-5-cyanothiophene;5-amino-2-Thiophenecarbonitrile;5-AMinothiophene-2-carbonitrile;2-Thiophenecarbonitrile, 5-amino-;5-Aminothiophene-2-carbonitrile - [A40782]
CBNumber: CB82733988
Molecular Formula: C5H4N2S
Formula Weight: 124.16
MOL File: 52532-63-5.mol

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5-AMinothiophene-2-carbonitrile Property

Boiling point:: 312.1±22.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: -0.37±0.10(Predicted)
Appearance: Off-white to brown Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: A578088
Product name: 5-Aminothiophene-2-carbonitrile
Packaging: 50mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA141143
Product name: 5-Aminothiophene-2-carbonitrile
Packaging: 100mg
Price: $136
Updated: 2021/12/16

AK Scientific

Product number: 7417AB
Product name: 5-Aminothiophene-2-carbonitrile
Packaging: 50mg
Price: $155
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA141143
Product name: 5-Aminothiophene-2-carbonitrile
Packaging: 50mg
Price: $78
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA141143
Product name: 5-Aminothiophene-2-carbonitrile
Packaging: 500mg
Price: $470
Updated: 2021/12/16

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5-AMinothiophene-2-carbonitrile Chemical Properties,Usage,Production

Synthesis

16689-02-4

52532-63-5

General procedure for the synthesis of 5-aminothiophene-2-carbonitrile from 5-nitrothiophene-2-carbonitrile: 5-nitrothiophene-2-carbonitrile (1 g, 6.5 mmol) was suspended in methanol (30 mL), aqueous NH4Cl (30 mL containing 4.5 g, 65 mmol) was added, followed by activated zinc (4.2 g, 65 mmol). The reaction mixture was stirred for 0.5 h at room temperature. After completion of the reaction, the mixture was filtered through a short diatomaceous earth pad and the filtrate was concentrated. The concentrated residue was partitioned between ethyl acetate and water. The organic layer was separated and the aqueous layer was further extracted with ethyl acetate. All organic extracts were combined, washed sequentially with water and brine, dried over MgSO4 and concentrated to give 5-aminothiophene-2-carbonitrile as a yellow solid (0.7 g, 87% yield).

References

[1] Patent: US2011/130398, 2011, A1. Location in patent: Page/Page column 79; 80
[2] Patent: US6353006, 2002, B1. Location in patent: Page column 146

5-AMinothiophene-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMinothiophene-2-carbonitrile Suppliers

China 34 India 1 United Kingdom 1 United States 2 Global 38

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52532-63-5, 5-AMinothiophene-2-carbonitrileRelated Search:

5-AMinothiophene-2-carbonitrile

5-amino-2-Thiophenecarbonitrile

2-Thiophenecarbonitrile, 5-amino-

2-Amino-5-cyanothiophene

5-Aminothiophene-2-carbonitrile - [A40782]

52532-63-5