ChemicalBook > CAS DataBase List > PHA-767491 (hydrochloride)

PHA-767491 (hydrochloride)

Product Name
PHA-767491 (hydrochloride)
CAS No.
942425-68-5
Chemical Name
PHA-767491 (hydrochloride)
Synonyms
PHA-767491 HCl ，S2742;CAY-10572 HYDROCHLORIDE;PHA-767491A hydrochloride;PHA-767491 hydrochloride, 10 mM in DMSO;CAY10572 (PHA-767491), Cdc7 and Cdk9 kinase inhibitor;2-(Pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
CBNumber
CB82735533
Molecular Formula
C12H12ClN3O
Formula Weight
249.7
MOL File
942425-68-5.mol
More
Less

PHA-767491 (hydrochloride) Property

storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO:20.0(Max Conc. mg/mL);80.1(Max Conc. mM)
form 
A crystalline solid
color 
Light yellow to yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
18218
Product name
PHA-767491 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
18218
Product name
PHA-767491 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$85
Updated
2024/03/01
Cayman Chemical
Product number
18218
Product name
PHA-767491 (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$186
Updated
2024/03/01
Cayman Chemical
Product number
18218
Product name
PHA-767491 (hydrochloride)
Purity
≥98%
Packaging
50mg
Price
$324
Updated
2024/03/01
ChemScene
Product number
CS-3865
Product name
PHA 767491 hydrochloride
Purity
99.91%
Packaging
50mg
Price
$355
Updated
2021/12/16
More
Less

PHA-767491 (hydrochloride) Chemical Properties,Usage,Production

Uses

PHA 767491 Hydrochloride (cas# 942425-68-5) is a useful research chemical used in the synthesis of heteroaryl-substituted pyrrolopyridinones and analogs as cdc7 kinase inhibitors and potential antitumor agents.

in vivo

PHA-767491 decreases Chk1 phosphorylation and increases in situ cell apoptosis in tumor tissues sectioned from nude mice HCC xenografts[2].

IC 50

CDK9: 34 nM (IC50); CDK2: 240 nM (IC50); CDK1: 250 nM (IC50); CDK5: 460 nM (IC50); GSK3-β: 220 nM (IC50); Mk2: 470 nM (IC50); Plk1: 980 nM (IC50); Chk2: 1100 nM (IC50)

storage

Desiccate at RT

PHA-767491 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PHA-767491 (hydrochloride) Suppliers

China 59 India 1 United Kingdom 1 United States 10 Global 71
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
8011
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29759
Advantage
68

942425-68-5, PHA-767491 (hydrochloride)Related Search:

5,6,7,8-TETRAHYDROISOQUINOLINE Lithium Aluminum Hydride Tetryzoline HYDROXYECTOINE 1,2,3,4-Tetrahydrocarbazole Tetrahydrofurfuryl alcohol Tetrahydropyran

  • CAY-10572 HYDROCHLORIDE
  • 2-(Pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
  • PHA-767491A hydrochloride
  • CAY10572 (PHA-767491), Cdc7 and Cdk9 kinase inhibitor
  • PHA-767491 hydrochloride, 10 mM in DMSO
  • PHA-767491 HCl ，S2742
  • 942425-68-5