L-DAB HBR
- Product Name
- L-DAB HBR
- CAS No.
- 1758-80-1
- Chemical Name
- L-DAB HBR
- Synonyms
- L-DABA;H-DabHBr;L-DAB HBR;H-Daba-OH.HBr;L-DAB HYDROBROMIDE;L-DAB HBR USP/EP/BP;L-2,4-diaminobutyrate;L-2,4-Diaminobutanoate;L-2,4-diaminobutyricaci;(S)-2,4-Diaminobutyric acid
- CBNumber
- CB8274119
- Molecular Formula
- C4H10N2O2
- Formula Weight
- 118.13
- MOL File
- 1758-80-1.mol
L-DAB HBR Property
- Melting point:
- 216-218 °C
- Boiling point:
- 321.0±32.0 °C(Predicted)
- Density
- 1.218±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- Powder
- pka
- 2.00±0.10(Predicted)
- color
- White to off-white
- CAS DataBase Reference
- 1758-80-1(CAS DataBase Reference)
Safety
- HS Code
- 2922498590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-6314
- Product name
- L-DABA
- Purity
- >98.0%
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- C7075
- Product name
- L-DABA
- Packaging
- 200mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- FD72503
- Product name
- L-Dab·HBr
- Packaging
- 2g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 180401
- Product name
- L-Dab·HBr
- Packaging
- 5g
- Price
- $143
- Updated
- 2021/12/16
- Product number
- C7075
- Product name
- L-DABA
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
L-DAB HBR Chemical Properties,Usage,Production
Uses
L-DABA (L-2,4-Diaminobutyric acid) is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.
Definition
ChEBI: A 2,4-diaminobutyric acid that has S-configuration.
in vivo
Treatment with L-DABA results in 43.4% reduction of tumor growth[1]. L-DABA is a more effective inhibitor of GABA transaminase in vivo than in vitro[2].
IC 50
Human Endogenous Metabolite
References
[1] Ronquist G, et al. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo. J Cancer Res Clin Oncol. 1980;96(3):259-68. DOI:10.1007/BF00408098
[2] Beart PM, et al. l-2,4-Diaminobutyric acid and the GABA system. Neurosci Lett. 1977 Jul;5(3-4):193-8. DOI:10.1016/0304-3940(77)90046-5
[3] Panasci L, et al. The cytolytic effect of L-2,4 diaminobutyric acid with malignant glioma cells and fibroblasts. Cancer Chemother Pharmacol. 1988;21(2):143-4. DOI:10.1007/BF00257361
L-DAB HBR Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-DAB HBR manufacturers
- Product
- L-2,4-diaminobutyric acid 1758-80-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26
- Product
- L-DAB HBR 1758-80-1
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2019-08-31