Doramectin aglycone
- Product Name
- Doramectin aglycone
- CAS No.
- 1987883-26-0
- Chemical Name
- Doramectin aglycone
- Synonyms
- Doramectin aglycone;25R-cyclohexyl-22,23-didehydro-5-O-demethyl-28-deoxy-6R,28-epoxy-13S-hydroxy-milbemycinB;Milbemycin B, 25-cyclohexyl-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-, (6R,13S,25R)-
- CBNumber
- CB82744539
- Molecular Formula
- C36H50O8
- Formula Weight
- 610.7774
- MOL File
- 1987883-26-0.mol
Doramectin aglycone Property
- Boiling point:
- 809.2±65.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- A solid
- pka
- 12.43±0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- 23655
- Product name
- Doramectin aglycone
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $332
- Updated
- 2024/03/01
- Product number
- 23655
- Product name
- Doramectin aglycone
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $1157
- Updated
- 2023/06/20
- Product number
- 1472EN
- Product name
- (1'R,2R,3S,4'S,6S,8'R,10'Z,12'S,13'S,14'Z,20'R,21'R,24'S)-2-Cyclohexyl-12',21',24'-trihydroxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
- Packaging
- 5mg
- Price
- $1412
- Updated
- 2021/12/16
- Product number
- 1472EN
- Product name
- (1'R,2R,3S,4'S,6S,8'R,10'Z,12'S,13'S,14'Z,20'R,21'R,24'S)-2-Cyclohexyl-12',21',24'-trihydroxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
- Packaging
- 1mg
- Price
- $503
- Updated
- 2021/12/16
Doramectin aglycone Chemical Properties,Usage,Production
Description
Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectin monosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone.
Uses
Doramectin aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of doramectin. Doramectin aglycone is an inhibitor of nematode larval development, but is devoid of paralytic activity. Despite the importance of doramectin as an anthelmintic in animal health, there are no published reports of the biological activity or the levels of doramectin aglycone in animals or in the environment.
Doramectin aglycone Preparation Products And Raw materials
Raw materials
Preparation Products
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