Macitentan impurity B

Product Name: Macitentan impurity B
CAS No.: 441796-13-0
Chemical Name: Macitentan impurity B
Synonyms: Macitentan impurity D;Macitentan impurity B;Macitentan Impurity 04;Macitentan N-Despropyl-N-Ethyl Impurity;Macitentan N-Despropyl-N-Ethyl Impurity/ Macitentan N-Ethyl Analog;5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine;Sulfamide, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-ethyl-
CBNumber: CB82747015
Molecular Formula: C18H18Br2N6O4S
Formula Weight: 574.25
MOL File: 441796-13-0.mol

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Macitentan impurity B Property

Boiling point:: 686.7±65.0 °C(Predicted)
Density: 1.715±0.06 g/cm3(Predicted)
pka: 6.90±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D297345
Product name: N-Despropyl-N-ethylMacitentan
Packaging: 2.5mg
Price: $210
Updated: 2021/12/16

TRC

Product number: D297345
Product name: N-Despropyl-N-ethylMacitentan
Packaging: 5mg
Price: $400
Updated: 2021/12/16

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Macitentan impurity B Chemical Properties,Usage,Production

Uses

N-Despropyl-N-ethyl Macitentan is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension.

Macitentan impurity B Preparation Products And Raw materials

Raw materials

Preparation Products

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Macitentan impurity B Suppliers

China 27 India 2 United Kingdom 1 United States 2 Global 32

Daicel Chiral Technologies (China)CO.,LTD

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441796-13-0, Macitentan impurity BRelated Search:

Macitidine related impurities PropylsulfaMide CarbaMic acid, N-[(propylaMino)sulfonyl]-, phenylMethyl ester 4(1H)-PyriMidinone, 5-(4-broMophenyl)-6-hydroxy- N-Propylsulfuric diamide-sodium SulfaMide, N-propyl-,(potassiuM salt)(1:1) Macitentan impurity A 5-Bromo-2-chloropyrimidine 5-(4-Bromophenyl)-4,6-dichloropyrimidine 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER macitentan Macitentan Impurity 13 Macitentan Impurity 17 Macitentan IMpurity ACT 080803 Macitentan Impurity 2 Macitentan Impurity 14 Macitentan Impurity 10

Macitentan impurity B

Macitentan impurity D

Macitentan N-Despropyl-N-Ethyl Impurity

Sulfamide, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-ethyl-

Macitentan N-Despropyl-N-Ethyl Impurity/ Macitentan N-Ethyl Analog

5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine

Macitentan Impurity 04

441796-13-0

C18H18Br2N6O4S