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Methyl-piperidino-pyrazole hydrate

Product Name
Methyl-piperidino-pyrazole hydrate
CAS No.
911295-24-4
Chemical Name
Methyl-piperidino-pyrazole hydrate
Synonyms
MPP dihydrochloride hydrate;Methyl-piperidino-pyrazole hydrate;MPP dihydrochloride (289726-02-9 Free base);Methyl-piperidino-pyrazole dihydrochloride hydrate;MPP dihydrochloride (289726029 Free base),MPP dihydrochloride (289726 02 9 Free base);4,4'-(4-Methyl-5-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-pyrazole-1,3-diyl)diphenol dihydrochloride;1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride hydrate
CBNumber
CB82750408
Molecular Formula
C29H32ClN3O3
Formula Weight
506.04
MOL File
911295-24-4.mol
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Methyl-piperidino-pyrazole hydrate Property

storage temp. 
Store at -20°C
solubility 
DMSO: soluble ≥20mg/mL
form 
white powder
color 
White to off-white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M7068
Product name
MPP dihydrochloride hydrate
Purity
≥97% (HPLC), white powder
Packaging
10mg
Price
$207
Updated
2024/03/01
Sigma-Aldrich
Product number
M7068
Product name
MPP dihydrochloride hydrate
Purity
≥97% (HPLC), white powder
Packaging
25mg
Price
$433
Updated
2024/03/01
TRC
Product number
M745858
Product name
MPPDihydrochloride
Packaging
10mg
Price
$145
Updated
2021/12/16
ApexBio Technology
Product number
B6910
Product name
MPPdihydrochloride
Packaging
10mg
Price
$266
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0027255
Product name
MPP DIHYDROCHLORIDE HYDRATE
Purity
95.00%
Packaging
5MG
Price
$502.62
Updated
2021/12/16
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Methyl-piperidino-pyrazole hydrate Chemical Properties,Usage,Production

Uses

MPP Dihydrochloride is a pharmacological estrogen receptor antagonist. It cannot block EE2 induced luciferase activity with any isoform of zebrafish estrogen receptor.

Uses

MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:

  • in human breast cancer MCF-7 cells
  • to pre-treat endometrial ex vivo organ cultures (EVOCs)
  • to treat pituitary glands to monitor luteinizing hormone secretion

General Description

Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol.

Biochem/physiol Actions

MPP dihydrochloride is a specific estrogen receptor α antagonist.

storage

+4°C (desiccate)

Methyl-piperidino-pyrazole hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl-piperidino-pyrazole hydrate Suppliers

Sigma-Aldrich
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911295-24-4, Methyl-piperidino-pyrazole hydrateRelated Search:


  • 1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride hydrate
  • MPP dihydrochloride hydrate
  • Methyl-piperidino-pyrazole hydrate
  • Methyl-piperidino-pyrazole dihydrochloride hydrate
  • MPP dihydrochloride (289726-02-9 Free base)
  • MPP dihydrochloride (289726029 Free base),MPP dihydrochloride (289726 02 9 Free base)
  • 4,4'-(4-Methyl-5-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-pyrazole-1,3-diyl)diphenol dihydrochloride
  • 911295-24-4