ChemicalBook > CAS DataBase List > Methyl-piperidino-pyrazole hydrate
Methyl-piperidino-pyrazole hydrate
- Product Name
- Methyl-piperidino-pyrazole hydrate
- CAS No.
- 911295-24-4
- Chemical Name
- Methyl-piperidino-pyrazole hydrate
- Synonyms
- MPP dihydrochloride hydrate;Methyl-piperidino-pyrazole hydrate;MPP dihydrochloride (289726-02-9 Free base);Methyl-piperidino-pyrazole dihydrochloride hydrate;MPP dihydrochloride (289726029 Free base),MPP dihydrochloride (289726 02 9 Free base);4,4'-(4-Methyl-5-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-pyrazole-1,3-diyl)diphenol dihydrochloride;1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride hydrate
- CBNumber
- CB82750408
- Molecular Formula
- C29H32ClN3O3
- Formula Weight
- 506.04
- MOL File
- 911295-24-4.mol
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Methyl-piperidino-pyrazole hydrate Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble ≥20mg/mL
- form
- white powder
- color
- White to off-white
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- M7068
- Product name
- MPP dihydrochloride hydrate
- Purity
- ≥97% (HPLC), white powder
- Packaging
- 10mg
- Price
- $207
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- M7068
- Product name
- MPP dihydrochloride hydrate
- Purity
- ≥97% (HPLC), white powder
- Packaging
- 25mg
- Price
- $433
- Updated
- 2024/03/01
TRC
- Product number
- M745858
- Product name
- MPPDihydrochloride
- Packaging
- 10mg
- Price
- $145
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B6910
- Product name
- MPPdihydrochloride
- Packaging
- 10mg
- Price
- $266
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0027255
- Product name
- MPP DIHYDROCHLORIDE HYDRATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.62
- Updated
- 2021/12/16
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Methyl-piperidino-pyrazole hydrate Chemical Properties,Usage,Production
Uses
MPP Dihydrochloride is a pharmacological estrogen receptor antagonist. It cannot block EE2 induced luciferase activity with any isoform of zebrafish estrogen receptor.
Uses
MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:
- in human breast cancer MCF-7 cells
- to pre-treat endometrial ex vivo organ cultures (EVOCs)
- to treat pituitary glands to monitor luteinizing hormone secretion
General Description
Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol.
Biochem/physiol Actions
MPP dihydrochloride is a specific estrogen receptor α antagonist.
storage
+4°C (desiccate)
Methyl-piperidino-pyrazole hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
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