ChemicalBook > CAS DataBase List > 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

Product Name
5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
CAS No.
1416324-85-0
Chemical Name
5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
Synonyms
CU-CPT22;CU-CPT22 >=98% (HPLC);hexyl 3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate;inhibit,CU CPT22,Inhibitor,CU-CPT22,Toll-like Receptor (TLR),CUCPT22,CU-CPT-22;3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester;5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
CBNumber
CB82750594
Molecular Formula
C19H22O7
Formula Weight
362.37
MOL File
1416324-85-0.mol
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5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester Property

Boiling point:
610.4±55.0 °C(Predicted)
Density 
1.336±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble20mg/mL, clear
pka
6.04±0.20(Predicted)
form 
Powder
color 
orange to dark red
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Safety

Hazard Codes 
N
Risk Statements 
50/53
Safety Statements 
60-61
RIDADR 
UN 3077 9 / PGIII
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15244
Product name
CU CPT 22
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
15244
Product name
CU CPT 22
Packaging
10mg
Price
$275
Updated
2024/03/01
Cayman Chemical
Product number
15244
Product name
CU CPT 22
Packaging
5mg
Price
$152
Updated
2024/03/01
Tocris
Product number
4884
Product name
CUCPT22
Purity
≥98%(HPLC)
Packaging
10
Price
$266
Updated
2021/12/16
Tocris
Product number
4884
Product name
CUCPT22
Purity
≥98%(HPLC)
Packaging
50
Price
$1055
Updated
2021/12/16
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5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester Chemical Properties,Usage,Production

Description

CU CPT 22 is an antagonist of toll-like receptor 1 (TLR1) and TLR2 heterodimers (TLR1/TLR2; Ki = 0.41 μM). It inhibits nitric oxide (NO) production induced by the TLR2 agonist Pam3CSK4 in RAW 264.7 cells (IC50 = 0.58 μM). It is selective for TLR1/TLR2 over TLR2/TLR6 and TLR3, -4, and -7 homodimers, as well as 10 kinases at 0.5 μM. CU CPT 22 (8 μM) inhibits Pam3CSK4-induced release of TNF-α and IL-1β in RAW 264.7 cells by 60 and 95%, respectively.

storage

Store at -20°C

5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester Suppliers

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1416324-85-0, 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl esterRelated Search:


  • hexyl 3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate
  • 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
  • CU-CPT22
  • 3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester
  • CU-CPT22 >=98% (HPLC)
  • inhibit,CU CPT22,Inhibitor,CU-CPT22,Toll-like Receptor (TLR),CUCPT22,CU-CPT-22
  • 1416324-85-0