1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide

Product Name: 1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide
CAS No.: 1255516-86-9
Chemical Name: 1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide
Synonyms: MS-1020;MS-1020 >=98% (HPLC);1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphtamide;1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]naphthalene-2-carboxamide;1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide;2-Naphthalenecarboxamide, 1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-
CBNumber: CB82750655
Molecular Formula: C21H18N2O3
Formula Weight: 346.38
MOL File: 1255516-86-9.mol

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1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide Property

storage temp.: 2-8°C
solubility: DMSO: ≥10mg/mL at 60°C
form: powder
color: white to tan

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Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0204
Product name: MS-1020
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $404
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0204
Product name: MS-1020
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $113
Updated: 2022/05/15

Cayman Chemical

Product number: 14273
Product name: MS-1020
Purity: ≥95%
Packaging: 1mg
Price: $93
Updated: 2024/03/01

Usbiological

Product number: 045047
Product name: MS-1020
Packaging: 1mg
Price: $303
Updated: 2021/12/16

Adipogen Life Sciences

Product number: AG-CR1-3501-M001
Product name: MS-1020
Purity: ≥95%(NMR)
Packaging: 1mg
Price: $65
Updated: 2021/12/16

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1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide Chemical Properties,Usage,Production

Description

MS-1020 is a cell-permeable inhibitor of janus kinase 3 (JAK3), strongly inhibiting constitutive autophosphorylation of JAK3 in L540 cells when used at 30-50 μM. It is without effect on other JAK isoforms and several other kinases, including Src, Lyn, Akt, EGFR, and ERK1/2. Through its effects on JAK3, MS-1020 blocks phosphorylation of downstream signal transduction and activators of transcription isoforms, reducing the expression of anti-apoptotic genes, leading to cell death.

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide Suppliers

China 27 United States 6 Global 33

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6870
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

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Email: malulu@leyan.com
Country: China
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Advantage: 58

Energy Chemical

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Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
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Country: China
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Advantage: 58

Aladdin Scientific

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Country: United States
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Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
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Country: China
ProdList: 49739
Advantage: 58

1255516-86-9, 1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamideRelated Search:

1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphtamide

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-naphthalenecarboxamide

MS-1020

1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]naphthalene-2-carboxamide

2-Naphthalenecarboxamide, 1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-

MS-1020 >=98% (HPLC)

1255516-86-9