1-BOC-3,5-DIMETHYL-PIPERAZINE

Uses Description Source Background

Product Name: 1-BOC-3,5-DIMETHYL-PIPERAZINE
CAS No.: 129779-30-2
Chemical Name: 1-BOC-3,5-DIMETHYL-PIPERAZINE
Synonyms: cis-3;SOCS 3;IL-1F6;SOCS-3 human;Methisosildenafil-002-SR;Methisosildenafil-002-3R5S;1-BOC-3,5-DIMETHYL-PIPERAZINE;Methisosildenafil Impurity 30;cis-1-boc-3,5-dimethylpiperazine;1-BOC-CIS-3,5-DIMETHYL-PIPERAZINE
CBNumber: CB8277822
Molecular Formula: C11H22N2O2
Formula Weight: 214.3
MOL File: 129779-30-2.mol

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1-BOC-3,5-DIMETHYL-PIPERAZINE Property

Melting point:: 70-71°
Boiling point:: 279.7±15.0℃ (760 Torr)
Density: 0.970±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:: 123.0±20.4℃
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 8.58±0.60(Predicted)
form: solid
Appearance: White to off-white Solid
InChI: InChI=1/C11H22N2O2/c1-8-6-13(7-9(2)12-8)10(14)15-11(3,4)5/h8-9,12H,6-7H2,1-5H3/t8-,9+
InChIKey: NUZXPHIQZUYMOR-DTORHVGONA-N
SMILES: N1(C(OC(C)(C)C)=O)C[C@H](C)N[C@H](C)C1 |&1:9,12,r|

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Safety

Hazard Codes: N
Risk Statements: 36/37/38-50
Safety Statements: 26-61
RIDADR: UN3077

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B201325
Product name: 1-Boc-cis-3,5-dimethyl-piperazine
Packaging: 2.5g
Price: $205
Updated: 2021/12/16

Usbiological

Product number: 358975
Product name: SOCS3
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

Usbiological

Product number: 358974
Product name: SOCS3
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

Usbiological

Product number: 384461
Product name: SOCS3
Packaging: 96Tests
Price: $729
Updated: 2021/12/16

Usbiological

Product number: 145206
Product name: SOCS3
Packaging: 100ug
Price: $490
Updated: 2021/12/16

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1-BOC-3,5-DIMETHYL-PIPERAZINE Chemical Properties,Usage,Production

Uses

1-Boc-cis-3,5-dimethyl-piperazine is used in the identification of 7-(3-(Piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent, selective and orally bioavailable PI3Kδ inhibitors.

Description

1-BOC-3,5- dimethylpiperazine is a heterocyclic derivative and can be used as pharmaceutical intermediates.

Uses

1-Boc-cis-3,5-dimethyl-piperazine is used in the identification of 7-(3-(Piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent, selective and orally bioavailable PI3Kδ inhibitors.

Description

SOCS3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 262 amino acids (1-225 a.a) and having a molecular mass of 29kDa.SOCS3 is fused to a 37 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Suppressor of Cytokine Signaling 3, also known as SOCS3 belongs to the SOCS family; in addition SOCS3 is a member of the STAT-induced STAT inhibitor (SSI). The SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of SOCS3 is induced by different cytokines, including IL6 and IL10. SOCS3 can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of SOCS3 have shown the roles of SOCS3 in the negative regulation of fetal liver hematopoiesis, and placental development.

1-BOC-3,5-DIMETHYL-PIPERAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-3,5-DIMETHYL-PIPERAZINE Suppliers

China 103 India 1 United Kingdom 1 United States 20 Global 125

Nanjing Asfam Pharmaceutical Technology Co., Ltd.

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View Lastest Price from 1-BOC-3,5-DIMETHYL-PIPERAZINE manufacturers

Career Henan Chemical Co

Product: 1-BOC-3,5-DIMETHYL-PIPERAZINE 129779-30-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2020-01-08

129779-30-2, 1-BOC-3,5-DIMETHYL-PIPERAZINERelated Search:

tert-butyl (2R,6S)-2,6-dimethylpiperazine-1-carboxylate (Z)-2-Methoxyimino-2-(furyl-2-yl) acetic acid ammonium salt cis-2,6-Dimethylpiperazine 1-BOC-3,5-DIMETHYL-PIPERAZINE tert-butyl 3,8-diazabicyclo[3.2.1]octane-3-carboxylate 1-BOC-2,2-DIMETHYL-PIPERAZINE (2S,5R)-1-Boc-2,5-Dimethyl-Piperazine 1-BOC-2,6-DIMETHYL-PIPERAZINE (2R,5S)-1-Boc-2,5-Dimethyl-Piperazine (2S,5S)-1-Boc-2,5-Dimethyl-Piperazine (3R,5S)-3,5-DIETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (3S,5R)-3,5-DIBENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (3S,5S)-3,5-DIETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER AKOS 90227 (3S,5S)-3,5-DIBENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3-(4-METHOXY-PHENYL)-OCTAHYDRO-QUINOXALINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (3R,5R)-3,5-DIBENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (3S,5S)-3,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(3R,5S)-3,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

1-BOC-3,5-DIMETHYL-PIPERAZINE

1-BOC-CIS-3,5-DIMETHYL-PIPERAZINE

CIS-3,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

5-DiMethyl-piperazine-1-carboxylic acid tert-butyl ester

cis-3

1-Piperazinecarboxylic acid, 3,5-diMethyl-, 1,1-diMethylethyl ester, (3R,5S)-

(3R,5S)-rel-tert-Butyl 3,5-diMethylpiperazine-1-carboxylate

Cytokine-inducible SH2-containing protein-3

IL-1F6

SOCS 3

SOCS-3 human

Suppressor of cytokine signaling-3

cis-1-boc-3,5-dimethylpiperazine

Methisosildenafil-002-SR

Methisosildenafil-002-3R5S

(3S,5R)-3,5-dimethylpiperazine-1-carboxylic acid tert-butyl ester

Methisosildenafil Impurity 30

Cis-Tert-Butyl 3,5-Dimethylpiperazine-1-Carboxylate*

1-Piperazinecarboxylic acid, 3,5-dimethyl-, 1,1-dimethylethyl ester, (3R,5S)-rel-

tert-butyl cis-3,5-dimethylpiperazine-1-carboxylate

(3R,5S)-3,5-dimethyl-1-Boc-piperazine

rel-tert-butyl (3R,5S)-3,5-dimethylpiperazine-1-carboxylate

cis-1-Boc-3,5-dimethylpiperazine (Methisosildenafil Impurity)

1-Boc-3,5-dimethyl-piperazine, , 95%min

tert-butyl Rel-(3r,5s)-3,5-dimethylpiperazine-1-carboxylate

129779-30-2