7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE

Product Name: 7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE
CAS No.: 17771-33-4
Chemical Name: 7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE
Synonyms: 7-hydroxy-2,2-dimethyl-4-chromanone;2,2-Dimethyl-7-hydroxychroman-4-one;7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE;7-HYDROXY-2,2-DIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE;7-Hydroxy-2,2-dimethyl-3,4-dihydro-2h-1-benzopyran-4-one;2,3-Dihydro-7-hydroxy-2,2-dimethyl-4H-1-benzopyran-4-one;2,2-Dimethyl-7-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2,2-dimethyl-
CBNumber: CB8281656
Molecular Formula: C11H12O3
Formula Weight: 192.21
MOL File: 17771-33-4.mol

More

Less

7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE Property

Melting point:: 172 °C(Solv: ethanol (64-17-5))
Boiling point:: 354.3±42.0 °C(Predicted)
Density: 1.196±0.06 g/cm3(Predicted)
pka: 7.75±0.40(Predicted)
form: Solid
color: Off-white to pink

More

Less

Safety

HazardClass: IRRITANT
HS Code: 2932990090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B444368
Product name: 7-hydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one
Packaging: 250mg
Price: $240
Updated: 2021/12/16

Matrix Scientific

Product number: 064962
Product name: 7-Hydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one
Packaging: 5g
Price: $495
Updated: 2021/12/16

AK Scientific

Product number: 5940AD
Product name: 7-Hydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one
Packaging: 5g
Price: $718
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0114305
Product name: 7-HYDROXY-2,2-DIMETHYL-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE
Purity: 95.00%
Packaging: 1G
Price: $808.89
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0114305
Product name: 7-HYDROXY-2,2-DIMETHYL-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE
Purity: 95.00%
Packaging: 2.5G
Price: $1147.43
Updated: 2021/12/16

More

Less

7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE Chemical Properties,Usage,Production

Uses

7-Hydroxy-2,2-dimethyl-4-chromanone (compound 41) is an inhibitor of DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule 3 grabbing non-integrin), with an IC50 of 4.66 mM[1]. DC-SIGN is the C-type lectin receptor presenting on the surface of both macrophages and dendritic cells[2].

References

[1] Wang J, et al. Negative regulation of Toll-like receptor signaling pathway. Microbes Infect. 2009 Mar;11(3):321-7. DOI:10.1016/j.micinf.2008.12.011
[2] Aaftaab Sethi, et al. Non-carbohydrate strategies to inhibit lectin proteins with special emphasis on galectins. Eur J Med Chem. 2021 Oct 15:222:113561. DOI:10.1016/j.ejmech.2021.113561

7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE Suppliers

China 23 India 1 United Kingdom 2 United States 5 Global 31

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Shanghai URChem Limited

Tel: +86-021-50890968，021-50891159 +86-18601776121
Fax: 086-21-68416099 58604179
Email: danny@urchem.com
Country: China
ProdList: 628
Advantage: 58

DebyeTec.com Inc.

Tel: 18-086626237 18086626237
Fax: qq:2693528373
Email: 2693528373@qq.com
Country: China
ProdList: 2973
Advantage: 56

Tianjin Being Technology Co., Ltd.

Tel: 18622939839
Fax: QQ:343281693
Email: tjby921@163.com
Country: China
ProdList: 884
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing Nohon Biological Technology Co., Ltd.

Tel: 025-85767923 18512596075
Fax: 025-85767923
Email: sales@nuoxibio.com
Country: China
ProdList: 960
Advantage: 55

Biokitchen

Tel: 021-021-021-31663258 13795219287
Fax: 021-31663258
Email: donghuanwen@126.com
Country: China
ProdList: 8816
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Fax: 86-10-80339217
Email: 2559355526@qq.com
Country: China
ProdList: 14193
Advantage: 58

Zhengzhou Alfa Chemical Co.,Ltd

Tel: +8618530059196
Email: sale04@alfachem.cn
Country: China
ProdList: 11784
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 55000
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Yantai Zhengxin New Material Technology Co. LTD

Tel: 13854547682 13854547682
Email: 542660804@qq.com
Country: China
ProdList: 4525
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 9898
Advantage: 58

Heze Aiding Pharmaceutical Co., Ltd

Tel: 17661365138
Email: 2845578351@qq.com
Country: China
ProdList: 7115
Advantage: 58

PharmaBlock Sciences (Nanjing), Inc.

Tel: 4000255188
Email: sales@pharmablock.com
Country: China
ProdList: 7268
Advantage: 58

shanghaiaoderuikanglimitedcompany

Tel: 18902198068 18912886236
Email: akslichenglong@163.com
Country: China
ProdList: 538
Advantage: 58

Yantai Shengkailun Chemical Technology Co., Ltd.

Tel: 13356901049
Email: mark@sklnchem.cn
Country: China
ProdList: 9995
Advantage: 58

Jining Yize Pharmaceutical Technology Co., Ltd

Tel: 15192473210
Email: 302633902@qq.com
Country: China
ProdList: 4480
Advantage: 58

Hangzhou Sulfuchem Material Technology Co., Ltd.

Tel: 0571-86113725 15372021306
Email: sales@sulfuchem.com
Country: China
ProdList: 970
Advantage: 58

Suzhou ARTK Medchem Co., Ltd.

Tel: +86-512-68323658 +86-18168183658
Email: sales1@artkmedchem.com
Country: China
ProdList: 39002
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

Syntechem Co.,Ltd

Tel: --
Fax: --
Email: -
Country: China
ProdList: 6193
Advantage: 58

17771-33-4, 7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONERelated Search:

2,2-DIMETHYL-CHROMAN-4-ONE 6,7-DIMETHOXY-2,2-DIMETHYL-4-CHLOROMANONE 7-HYDROXY-2,2,8-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE 7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE 2,2-BIS(TRIFLUOROMETHYL)-7-METHOXYCHROMANE-4-ONE 2-Butenal, 2-methyl-4-[3a,4,5,7-tetrahydro-8-hydroxy-3,3,11,11-tetramethyl-13-(3-methyl-2-butenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-, [1R-[1alpha,1(Z),3abeta,5alpha,14aS*]]- GARCINOLIC ACID; TRANS-(SH) 7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE 2,2-DIMETHYL-7-PROPOXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE 6-(TERT-BUTYL)-7,8-DIHYDROXY-2,2-DIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE GAMBOGIC ACID 5,7-DIMETHOXY-2,2-DIMETHYL-CHROMAN-4-ONE 5,7-dihydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one

2,2-Dimethyl-7-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one

2,2-Dimethyl-7-hydroxychroman-4-one

2,3-Dihydro-7-hydroxy-2,2-dimethyl-4H-1-benzopyran-4-one

4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2,2-dimethyl-

7-hydroxy-2,2-dimethyl-4-chromanone

7-HYDROXY-2,2-DIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE

7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE

7-Hydroxy-2,2-dimethyl-3,4-dihydro-2h-1-benzopyran-4-one

17771-33-4