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2,3-DIMETHOXYBENZONITRILE

Product Name
2,3-DIMETHOXYBENZONITRILE
CAS No.
2024-83-1
Chemical Name
2,3-DIMETHOXYBENZONITRILE
Synonyms
AKOS B004317;VERATRONITRILE;4-CYANOVERATROLE;O-VERATRONITRILE;2-VERATRONITRILE;3-CYANOVERATROLE;AKOS BBS-00004470;LABOTEST-BB LT00159775;Vilanterol Impurity 71;3,4-DIMETHOXYBENZONITRILE
CBNumber
CB8288574
Molecular Formula
C9H9NO2
Formula Weight
163.17
MOL File
2024-83-1.mol
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2,3-DIMETHOXYBENZONITRILE Property

Melting point:
68-70 °C(lit.)
Boiling point:
290.25°C (rough estimate)
Density 
1.2021 (rough estimate)
refractive index 
1.5300 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in methanol.
form 
powder to crystal
color 
White to Light yellow
BRN 
1451651
InChI
1S/C9H9NO2/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-5H,1-2H3
InChIKey
OSEQIDSFSBWXRE-UHFFFAOYSA-N
SMILES
COc1ccc(cc1OC)C#N
CAS DataBase Reference
2024-83-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,T,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36
RIDADR 
3276
WGK Germany 
3
RTECS 
DI4355000
HazardClass 
6.1
PackingGroup 
III
HS Code 
2926907090
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D132306
Product name
3,4-Dimethoxybenzonitrile
Purity
≥99%
Packaging
25g
Price
$88.2
Updated
2025/07/31
TCI Chemical
Product number
D2870
Product name
3,4-Dimethoxybenzonitrile
Purity
>98.0%(GC)
Packaging
25g
Price
$257
Updated
2025/07/31
TRC
Product number
D525965
Product name
3,4-Dimethoxybenzonitrile
Packaging
25g
Price
$220
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0022705
Product name
3,4-DIMETHOXY BENZONITRILE
Purity
95.00%
Packaging
100G
Price
$2408.96
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0022705
Product name
3,4-DIMETHOXY BENZONITRILE
Purity
95.00%
Packaging
25G
Price
$1071.51
Updated
2021/12/16
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2,3-DIMETHOXYBENZONITRILE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

3,4-Dimethoxybenzonitrile is used as an organic chemical synthesis intermediate.

Preparation

Veratraldoxime(88–89 g, 0.45 mol) was combined with acetic anhydride (100 g) in a 300-mL round-bottomed flask equipped with a ground-glass air condenser, and the mixture was cautiously heated. A vigorous reaction took place, at which point the flame (heating by oil bath; the author) was removed. After the reaction had subsided, the solution was gently refluxed for 2 h and then carefully poured, with stirring, into cold water (300 mL). Stirring was continued, and on cooling the nitrile separated as small, almost colorless crystals; these were collected by filtration and dried in air. The veratronitrile thus obtained was quite pure; yield 57–62 g (72–76%); mp 66–67 C°.

1-Cyanoacenaphthene 1403 can be synthesized from its carbaldoxime by dehydration with acetic anhydride in 87% yield. Whereas acetic anhydride usually serves as the solvent as well as the reactant, this procedure is performed in n-octane.

Synthesis Reference(s)

Synthesis, p. 510, 1985 DOI: 10.1055/s-1985-31253

2,3-DIMETHOXYBENZONITRILE Preparation Products And Raw materials

Raw materials

3,4-dimethoxybenzaldehyde oxime Hydroxylamine hydrochloride

Preparation Products

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2,3-DIMETHOXYBENZONITRILE Suppliers

Americas 1 Belgium 2 China 154 Europe 3 France 2 Germany 5 India 19 Japan 4 Poland 1 Slovakia 1 South Korea 1 Switzerland 1 The Netherlands 2 Ukraine 1 United Kingdom 18 United States 30 Global 245
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
ProdList
96815
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New Energy Chemicals
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0515-82159099 13770142076
Fax
86-0515-8215909
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info@njuchem.com
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China
ProdList
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
ProdList
30123
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
Fax
021-67121385
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Sales-CN@TCIchemicals.com
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China
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24529
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ShangHai DEMO Chemical Co.,Ltd
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400-021-7337 2355568890
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0086-21-50182339
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sales@demochem.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
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86-027-87531808
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sales@chemwish.com
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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China
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
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+86-21-54098501
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+86-21-54096319
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sales@sinch.com.cn
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China
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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China
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View Lastest Price from 2,3-DIMETHOXYBENZONITRILE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2,3-DIMETHOXYBENZONITRILE 2024-83-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-18
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Apremilast Impurity 59 2024-83-1
Price
US $0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-03
Shanghai UCHEM Inc.
Product
Veratronitrile 2024-83-1
Price
US $12.00-151.00/g
Min. Order
25g
Purity
0.98
Supply Ability
25kg
Release date
2023-12-20

2024-83-1, 2,3-DIMETHOXYBENZONITRILERelated Search:

3,4,5-Trimethoxybenzonitrile 4,5-DIMETHOXY-2-NITROBENZONITRILE 4-BENZYLOXY-3-METHOXY-BENZONITRILE 2,3,4-TRIMETHOXYBENZONITRILE 2-AMINO-4,5-DIMETHOXYBENZONITRILE,2-AMINO-4 5-DIMETHOXYBENZONITRILE 96%,2-AMINO-4,5-DIMETHOXYBENZONITRILE TECHN. 95% 2,3-DIHYDRO-1,4-BENZODIOXINE-6-CARBONITRILE 2,3-DIMETHOXYBENZONITRILE 2-CHLORO-3,4-DIMETHOXYBENZONITRILE 3,2-DIMETHOXYBENZONITRILE,2,3-DIMETHOXYBENZONITRILE 2,6-DIMETHOXYBENZONITRILE 2-FLUORO-6-DIMETHOXYBENZONITRILE 2,4-DIMETHOXYBENZONITRILE 2,5-DIMETHOXYBENZONITRILE 3,5-DIMETHOXYBENZONITRILE,3,5-DIMETHOXYBENZONITRILE / 3,5-DIMETHOXYLPHENYL CYANIDE 2,4,5-TRIMETHOXYBENZONITRILE 2,2,3,3-Tetrafluoro-6-nitrilobenzodioxene 2-FLUORO-4,5-DIMETHOXYBENZONITRILE, 98.0+%(GC),2-Fluoro-4,5-dimethoxybenzonitrile 3-(CYCLOPENTYLOXY)-4-METHOXYBENZONITRILE

  • LABOTEST-BB LT00159775
  • BENZONITRILE, 2,3-DIMETHOXY-
  • AKOS BBS-00004470
  • AKOS B004317
  • 3-CYANOVERATROLE
  • 3,4-DIMETHOXYBENZONITRILE
  • 4-CYANO-1,2-DIMETHOXYBENZENE
  • 4-CYANOVERATROLE
  • 3,2-DIMETHOXYBENZONITRILE
  • 2-VERATRONITRILE
  • O-VERATRONITRILE
  • VERATRONITRILE
  • 2,3-DIMETHOXYBENZONITRILE
  • 3.4-Dimethoxybenzonitrile,98%
  • 3,4-Dimethoxy-benzonitril
  • 3,4-DIMETHOXYBENZONITRILE, 99+%
  • 3,4-Dimethoxybenzonitrile97.5%
  • 3,4-DIMETHOXYBENZONITRILE / 3,4-DIMETHOXYLPHENYL CYANIDE
  • 3,4-dimethoxybenzene-carbonitrile
  • 4-Cyano-1,2-dimethoxybenzene 4-Cyanoveratrole
  • 3,4-Dimethoxybenzonitrile,97%
  • Benzonitrile, 3,4-diMethoxy-
  • 4-Cyanoveratrole, Veratronitrile
  • 3,4-Dimethoxybenzonitrile Verapamil, Denopamine
  • Veratronitrile (3,4-Dimethoxy Benzonitrile)
  • 3,4-Dimethoxybenzonitrile&gt
  • 1-cyano-3,4-dimethoxylbenzene
  • 3,4-Dimethoxy benzonitrile- 99% (Veratronitrile)
  • 2,3-DIMETHOXYBENZONITRILE,2024-83-1
  • Vilanterol Impurity 71
  • 2024-83-1
  • Cyanides/Nitriles
  • Organic Building Blocks
  • Nitrogen Compounds
  • C8 to C9
  • Building Blocks
  • Verapamil/Denopamine
  • Building Blocks
  • C8 to C9
  • Chemical Synthesis
  • Nitrogen Compounds
  • Organic Building Blocks
  • Phenyls & Phenyl-Het
  • C8 to C9
  • Cyanides/Nitriles
  • Nitrogen Compounds
  • Aromatic Nitriles
  • Phenyls & Phenyl-Het
  • Nitrile
  • Anisoles, Alkyloxy Compounds & Phenylacetates
  • Nitriles