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2-AMINO-4-CHLOROBENZOIC ACID

Product Name
2-AMINO-4-CHLOROBENZOIC ACID
CAS No.
5900-58-3
Chemical Name
2-AMINO-4-CHLOROBENZOIC ACID
Synonyms
METHYL 2-AMINO-4-CHLOROBENZOATE;2,4-ACBA;TIMTEC-BB SBB003711;RARECHEM AL BO 0400;LABOTEST-BB LT00454298;2-Amino-4-chlorobenzoic;2-CARBOXY-5-CHLOROANILINE;METHYL 4-CHLOROANTHRANILATE;4-CHLORO-2-AMINOBENZOIC ACID;3-AMINO-4-CARBOXY-1-CHLOROBENZENE
CBNumber
CB8290117
Molecular Formula
C8H8ClNO2
Formula Weight
185.61
MOL File
5900-58-3.mol
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2-AMINO-4-CHLOROBENZOIC ACID Property

Melting point:
66-71 °C
Boiling point:
284.0±20.0 °C(Predicted)
Density 
1.311±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
solid
pka
1.33±0.10(Predicted)
color 
Light brown
BRN 
1072895
InChI
InChI=1S/C8H8ClNO2/c1-12-8(11)6-3-2-5(9)4-7(6)10/h2-4H,10H2,1H3
InChIKey
YPSSCICDVDOEAI-UHFFFAOYSA-N
SMILES
C(OC)(=O)C1=CC=C(Cl)C=C1N
CAS DataBase Reference
5900-58-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
DG1570000
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M3605
Product name
Methyl 2-Amino-4-chlorobenzoate
Purity
min. 98.0 %
Packaging
5G
Price
$48
Updated
2025/07/31
TCI Chemical
Product number
M3605
Product name
Methyl 2-Amino-4-chlorobenzoate
Purity
min. 98.0 %
Packaging
25G
Price
$144
Updated
2025/07/31
TRC
Product number
M331640
Product name
Methyl2-Amino-4-chlorobenzoate
Packaging
1g
Price
$60
Updated
2021/12/16
TRC
Product number
M331640
Product name
Methyl2-Amino-4-chlorobenzoate
Packaging
5g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
O104
Product name
Methyl2-amino-4-chlorobenzoate
Packaging
5g
Price
$14
Updated
2021/12/16
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2-AMINO-4-CHLOROBENZOIC ACID Chemical Properties,Usage,Production

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1285, 1946 DOI: 10.1021/ja01211a049

Synthesis

67-56-1

89-77-0

5900-58-3

To a single-necked flask was added 10 g of 2-amino-4-chlorobenzoic acid and 150 ml of methanol, and the mixture was cooled to 0-5 °C. 10.4 g of thionyl chloride was slowly added dropwise with stirring. After the dropwise addition, the reaction mixture was heated to reflux for 24 hours. After completion of the reaction, it was cooled to room temperature and methanol was removed by distillation under reduced pressure. To the residue, 100 ml of ethyl acetate and 100 ml of 5% sodium carbonate solution were added, stirred thoroughly and left to stratify. The aqueous layer was separated and the organic layer was washed with 100 ml of water. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 8.9 g of methyl 2-amino-4-chlorobenzoate in 82% yield.

References

[1] Journal of Medicinal Chemistry, 1996, vol. 39, # 17, p. 3248 - 3255
[2] Patent: CN106243046, 2016, A. Location in patent: Paragraph 0047; 0052; 0053; 0073; 0074
[3] Patent: CN107778229, 2018, A. Location in patent: Paragraph 0021
[4] Patent: WO2010/65134, 2010, A1. Location in patent: Page/Page column 60
[5] Journal of the Chemical Society, 1947, p. 808,811

2-AMINO-4-CHLOROBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4-CHLOROBENZOIC ACID Suppliers

Belgium 1 China 147 Europe 4 France 1 Germany 7 India 8 Japan 3 Slovakia 1 Switzerland 4 Ukraine 2 United Kingdom 15 United States 44 Global 237
DOTTIKON EXCLUSIVE SYNTHESIS AG
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Switzerland
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6896
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Rohnerchem
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Biosynth AG
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welcome@biosynth.ch
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View Lastest Price from 2-AMINO-4-CHLOROBENZOIC ACID manufacturers

Career Henan Chemical Co
Product
2-AMINO-4-CHLOROBENZOIC ACID 5900-58-3
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-09

5900-58-3, 2-AMINO-4-CHLOROBENZOIC ACIDRelated Search:

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  • LABOTEST-BB LT00454298
  • METHYL 4-CHLOROANTHRANILATE
  • METHYL 2-AMINO-4-CHLOROBENZOATE
  • 2,4-ACBA
  • 2-CARBOXY-5-CHLOROANILINE
  • 2-AMINO-4-CHLOROBENZOIC ACID METHYL ESTER
  • 3-AMINO-4-CARBOXY-1-CHLOROBENZENE
  • 4-CHLOROANTHRANILIC ACID METHYL ESTER
  • 4-CHLORO-2-AMINOBENZOIC ACID
  • TIMTEC-BB SBB003711
  • Benzoic acid,2-amino-4-chloro-, methyl ester
  • RARECHEM AL BO 0400
  • 2-Amino-4-chlorobenzoic
  • Methyl 4-amino-2-chlorobenzoic acid
  • methyl 2-azanyl-4-chloro-benzoate
  • Methyl 2-AMino-4-chlorobenzoate, 97+%
  • 5900-58-3
  • Unnatural Amino Acid Derivatives
  • Peptide Synthesis
  • Specialty Synthesis
  • Aromatic Amino Acids
  • FINE Chemical & INTERMEDIATES
  • Aromatic Esters
  • Phenylacetic acid